用于活组织中过氧化氢的比率成像的双光子荧光探针。
A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue.
机构信息
Department of Chemistry, Korea University, 1-Anamdong, Seoul, 136-701, Korea.
Department of Chemistry and the Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA.
出版信息
Chem Commun (Camb). 2011 Sep 14;47(34):9618-9620. doi: 10.1039/c1cc13583j. Epub 2011 Jul 27.
Abstract
We report a two-photon fluorescent probe (PN1) that can be excited by 750 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize H(2)O(2) distribution in live cells and tissue by two-photon microscopy.
摘要
我们报道了一种双光子荧光探针（PN1），它可以被 750nm 的皮秒脉冲激发，具有高的光稳定性和可忽略的毒性，可以通过双光子显微镜观察活细胞和组织中的 H2O2 分布。
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