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伴巨大淋巴结病的窦性组织细胞增生症(罗萨伊-多夫曼病)的治疗

The treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease).

作者信息

Komp D M

机构信息

Department of Pediatrics, Yale University School of Medicine, New Haven, CT.

出版信息

Semin Diagn Pathol. 1990 Feb;7(1):83-6.

PMID:2180015
Abstract

The available information on treatment of sinus histiocytosis with massive lymphadenopathy (SHML) was reviewed. Treatment is not necessary in most instances, but some patients may require surgery, radiation therapy, and/or chemotherapy because of severe disease manifestations. An ideal treatment has yet to be identified. Of the various chemotherapeutic regimens that have been tried so far, a combination of vinca alkaloid, alkylating agent, and corticosteroid appears to be the most effective.

摘要

对窦组织细胞增生伴巨大淋巴结病(SHML)的现有治疗信息进行了综述。在大多数情况下无需治疗,但由于严重的疾病表现,一些患者可能需要手术、放射治疗和/或化疗。尚未确定理想的治疗方法。在迄今为止尝试过的各种化疗方案中,长春花生物碱、烷化剂和皮质类固醇的联合使用似乎是最有效的。

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