Komp D M
Department of Pediatrics, Yale University School of Medicine, New Haven, CT.
Semin Diagn Pathol. 1990 Feb;7(1):83-6.
The available information on treatment of sinus histiocytosis with massive lymphadenopathy (SHML) was reviewed. Treatment is not necessary in most instances, but some patients may require surgery, radiation therapy, and/or chemotherapy because of severe disease manifestations. An ideal treatment has yet to be identified. Of the various chemotherapeutic regimens that have been tried so far, a combination of vinca alkaloid, alkylating agent, and corticosteroid appears to be the most effective.
对窦组织细胞增生伴巨大淋巴结病(SHML)的现有治疗信息进行了综述。在大多数情况下无需治疗,但由于严重的疾病表现,一些患者可能需要手术、放射治疗和/或化疗。尚未确定理想的治疗方法。在迄今为止尝试过的各种化疗方案中,长春花生物碱、烷化剂和皮质类固醇的联合使用似乎是最有效的。