University of Liverpool Institute of Infection and Global Health, Liverpool, UK.
Emerg Infect Dis. 2011 Aug;17(8):1484-7. doi: 10.3201/eid1708.110165.
To investigate whether uncharacterized infectious agents were associated with neurologic disease, we analyzed cerebrospinal fluid specimens from 12 children with acute central nervous system infection. A high-throughput pyrosequencing screen detected human parvovirus 4 DNA in cerebrospinal fluid of 2 children with encephalitis of unknown etiology.
为了探究是否存在未明传染性病原体与神经疾病相关,我们分析了 12 位患有急性中枢神经系统感染的儿童的脑脊液样本。高通量焦磷酸测序筛查发现 2 位病因不明脑炎患儿的脑脊液中存在人细小病毒 4 型 DNA。