Cho Eun A, Oh Hyun Ei
Department of Nursing, Honam University, Gwangju, Korea.
J Korean Acad Nurs. 2011 Jun;41(3):285-93. doi: 10.4040/jkan.2011.41.3.285.
In this study, the effects of laughter therapy on levels of depression, quality of life, resilience and immune responses in breast cancer survivors were examined.
A quasi-experimental nonequivalent control group, pretest-posttest design was used. Participants (n=37) included breast cancer survivors who finished chemotheraphy and radiation therapy: 16 in the experiment group and 21 in the control group. Data were collected from August to November 2009. The experimental group participated in laughter therapy eight times, twice a week for 60 min per session. Questionnaires were used to measure pretest and posttest levels of depression, quality of life and resilience. A blood test was used to analyze changes in Total T cell, T helper, T suppressor, Th/Ts ratio, Total B cell, T cell/B cell ratio and NK cell for immune responses.
The results showed that laughter therapy was effective in increasing the quality of life and resilience in breast cancer survivors. but depression and immune responses did not differ significantly between the groups.
The results of the study indicate that laughter therapy may be an effective nursing intervention to improve quality of life and resilience in breast cancer survivors.
本研究探讨了欢笑疗法对乳腺癌幸存者抑郁水平、生活质量、心理弹性和免疫反应的影响。
采用类实验非等效对照组前测-后测设计。参与者（n = 37）为完成化疗和放疗的乳腺癌幸存者：实验组16人，对照组21人。数据于2009年8月至11月收集。实验组参加了8次欢笑疗法，每周两次，每次60分钟。使用问卷测量抑郁、生活质量和心理弹性的前测和后测水平。通过血液检测分析免疫反应中总T细胞、辅助性T细胞、抑制性T细胞、Th/Ts比值、总B细胞、T细胞/B细胞比值和自然杀伤细胞的变化。
结果表明，欢笑疗法可有效提高乳腺癌幸存者的生活质量和心理弹性。但两组之间的抑郁和免疫反应无显著差异。
研究结果表明，欢笑疗法可能是一种有效的护理干预措施，可改善乳腺癌幸存者的生活质量和心理弹性。
