Gregori Mario, Paneni Francesco, D'Agostino Michela, Tocci Giuliano, Ferrucci Andrea, Savoia Carmine
Division of Cardiology, Department of Clinical and Molecular Medicine, University of Rome "Sapienza", Sant'Andrea Hospital, Italy.
High Blood Press Cardiovasc Prev. 2011 Jun 1;18(2):57-9. doi: 10.2165/11593430-000000000-00000.
Pheochromocytoma is a neuroendocrine tumour of the adrenal gland that secretes an excessive amount of catecholamines, leading to a rapid rise and fall in blood pressure, headache, sweating and palpitations. The clinical scenario of pheochromocytoma, however, may be extremely variable and may include atypical cardiovascular manifestations, eventually leading to delays or mistakes in diagnosis. This issue is crucial since a missed diagnosis of pheochromocytoma may imply fatal consequences. This article reports a case of pheochromocytoma presenting with quite atypical cardiovascular manifestations such as transient left ventricular dysfunction and ventricular tachycardia. The pathophysiological determinants underlying uncommon clinical presentations of pheochromocytoma are also discussed. Received for publication 19 May 2011; accepted for publication 10 June 2011.
嗜铬细胞瘤是一种肾上腺神经内分泌肿瘤，可分泌过量的儿茶酚胺，导致血压迅速上升和下降、头痛、出汗及心悸。然而，嗜铬细胞瘤的临床症状可能极具变异性，可能包括非典型心血管表现，最终导致诊断延迟或误诊。这个问题至关重要，因为嗜铬细胞瘤漏诊可能意味着致命后果。本文报告了一例表现为相当非典型心血管症状（如短暂性左心室功能障碍和室性心动过速）的嗜铬细胞瘤病例。文中还讨论了嗜铬细胞瘤不常见临床表现背后的病理生理决定因素。于2011年5月19日收稿；2011年6月10日接受发表。
