Nanotechnology. 2008 Jun 18;19(24):245704. doi: 10.1088/0957-4484/19/24/245704. Epub 2008 May 12.
The deposition of plasma polymer coatings onto porous alumina (PA) membranes was investigated with the aim of adjusting the surface chemistry and the pore size of the membranes. PA membranes from commercial sources with a range of pore diameters (20, 100 and 200 nm) were used and modified by plasma polymerization using n-heptylamine (HA) monomer, which resulted in a chemically reactive polymer surface with amino groups. Heptylamine plasma polymer (HAPP) layers with a thickness less than the pore diameter do not span the pores but reduce their diameter. Accordingly, by adjusting the deposition time and thus the thickness of the plasma polymer coating, it is feasible to produce any desired pore diameter. The structural and chemical properties of modified membranes were studied by scanning electron microscopy (SEM), atomic force microscopy (AFM) and x-ray electron spectroscopy (XPS). The resultant PA membranes with specific surface chemistry and controlled pore size are applicable for molecular separation, cell culture, bioreactors, biosensing, drug delivery, and engineering complex composite membranes.
将等离子体聚合物涂层沉积到多孔氧化铝（PA）膜上，目的是调节膜的表面化学性质和孔径。使用了具有一系列孔径（20、100 和 200nm）的商业来源的 PA 膜，并通过使用正庚胺（HA）单体的等离子体聚合进行改性，从而得到具有氨基的反应性聚合物表面。厚度小于孔径的正庚胺等离子体聚合物（HAPP）层不会跨越孔，但会减小其直径。因此，通过调整沉积时间和等离子体聚合物涂层的厚度，可以生产出任何所需的孔径。通过扫描电子显微镜（SEM）、原子力显微镜（AFM）和 X 射线电子能谱（XPS）研究了改性膜的结构和化学性质。具有特定表面化学性质和受控孔径的所得 PA 膜适用于分子分离、细胞培养、生物反应器、生物传感、药物输送和工程复杂复合膜。
