非编码DNA的转录：多种途径通向局部基因调控。
Transcription of ncDNA: Many roads lead to local gene regulation.
作者信息
Hainer Sarah J, Martens Joseph A
机构信息
Department of Biological Sciences; University of Pittsburgh; Pittsburgh, PA USA.
出版信息
Transcription. 2011 May;2(3):120-123. doi: 10.4161/trns.2.3.15684.
Abstract
Transcription of ncDNA occurs throughout eukaryotic genomes, generating a wide array of ncRNAs. One large class of ncRNAs includes those transcribed over the promoter regions of nearby protein coding genes. Recent studies, primarily focusing on individual genes have uncovered multiple mechanisms by which promoter-associated transcriptional activity locally alters gene expression.
摘要
非编码DNA（ncDNA）的转录发生在整个真核生物基因组中，产生各种各样的非编码RNA（ncRNA）。一大类ncRNA包括那些在附近蛋白质编码基因的启动子区域转录的RNA。最近的研究主要集中在个别基因上，发现了多种机制，通过这些机制，启动子相关的转录活性在局部改变基因表达。
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