使用新一代自适应光学扫描激光检眼镜对正常受试者和患者的视锥和视杆光感受器进行观察。
Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope.
作者信息
Merino David, Duncan Jacque L, Tiruveedhula Pavan, Roorda Austin
出版信息
Biomed Opt Express. 2011 Aug 1;2(8):2189-201. doi: 10.1364/BOE.2.002189. Epub 2011 Jul 8.
Abstract
We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed on AOSLO images from two different diseased eyes, one affected by achromatopsia and the other by acute zonal occult outer retinopathy (AZOOR). The potential of AOSLO technology in the study of these and other retinal diseases is illustrated.
摘要
我们展示了新一代自适应光学扫描激光检眼镜（AOSLO）分辨正常受试者视锥细胞和视杆细胞的能力，并通过将视锥细胞和视杆细胞间距与已发表的组织学测量结果进行比较来证实我们的发现。还对来自两只不同患病眼睛的AOSLO图像进行了视锥细胞和视杆细胞间距测量，一只眼睛患有全色盲，另一只眼睛患有急性区域性隐匿性外层视网膜病变（AZOOR）。阐述了AOSLO技术在研究这些及其他视网膜疾病方面的潜力。
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