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人眼视杆细胞外节的活体成像。

In vivo imaging of the human rod photoreceptor mosaic.

机构信息

Center for Visual Science, University of Rochester, Rochester, New York 14627, USA.

出版信息

Opt Lett. 2011 Jan 1;36(1):31-3. doi: 10.1364/OL.36.000031.

DOI:10.1364/OL.36.000031
PMID:21209677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3125116/
Abstract

Although single cone receptors have been imaged , to our knowledge there has been no observation of rods in the living normal eye. Using an adaptive optics ophthalmoscope and post processing, evidence of a rod mosaic was observed at 5° and 10° eccentricities in the horizontal temporal retina. For four normal human subjects, small structures were observed between the larger cones and were observed repeatedly at the same locations on different days, and with varying wavelengths. Image analysis gave spacings that agree well with rod measurements from histological data.

摘要

虽然已经对单个视锥细胞进行了成像,但据我们所知,在正常活体眼中还没有观察到视杆细胞。使用自适应光学眼底镜和后处理技术,在水平颞视网膜的 5°和 10°偏心率处观察到了视杆细胞马赛克的证据。对于四个正常的人类受试者,在较大的视锥细胞之间观察到了较小的结构,并且在不同的日子、不同的波长下,在相同的位置上可以重复观察到这些结构。图像分析给出的间距与组织学数据中的视杆细胞测量值非常吻合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b17e/3125116/f995ddd301b8/nihms295248f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b17e/3125116/42dc7f8212c8/nihms295248f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b17e/3125116/f995ddd301b8/nihms295248f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b17e/3125116/42dc7f8212c8/nihms295248f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b17e/3125116/f995ddd301b8/nihms295248f2.jpg

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本文引用的文献

1
Spectral reflectance of the human ocular fundus.人眼眼底的光谱反射率。
Appl Opt. 1989 Mar 15;28(6):1061-77. doi: 10.1364/AO.28.001061.
2
Adaptive optics scanning laser ophthalmoscopy.自适应光学扫描激光检眼镜
Opt Express. 2002 May 6;10(9):405-12. doi: 10.1364/oe.10.000405.
3
In vivo imaging of the photoreceptor mosaic of a rod monochromat.视杆单色患者光感受器镶嵌的体内成像。
Vision Res. 2008 Nov;48(26):2564-8. doi: 10.1016/j.visres.2008.04.006. Epub 2008 May 21.
4
Effect of wavelength on in vivo images of the human cone mosaic.波长对人视锥细胞镶嵌的体内图像的影响。
J Opt Soc Am A Opt Image Sci Vis. 2005 Dec;22(12):2598-605. doi: 10.1364/josaa.22.002598.
5
The locus of fixation and the foveal cone mosaic.注视位点与中央凹视锥细胞镶嵌结构
J Vis. 2005 Aug 17;5(7):632-9. doi: 10.1167/5.7.3.
6
Supernormal vision and high-resolution retinal imaging through adaptive optics.通过自适应光学实现超常视觉和高分辨率视网膜成像。
J Opt Soc Am A Opt Image Sci Vis. 1997 Nov;14(11):2884-92. doi: 10.1364/josaa.14.002884.
7
Guidelines on limits of exposure to broad-band incoherent optical radiation (0.38 to 3 microM). International Commission on Non-Ionizing Radiation Protection.宽带非相干光辐射(0.38至3微米)暴露限值指南。国际非电离辐射防护委员会。
Health Phys. 1997 Sep;73(3):539-54.
8
Photoreceptor loss in age-related macular degeneration.年龄相关性黄斑变性中的光感受器丧失。
Invest Ophthalmol Vis Sci. 1996 Jun;37(7):1236-49.
9
Improvements on Littmann's method of determining the size of retinal features by fundus photography.对利特曼通过眼底摄影确定视网膜特征大小方法的改进。
Graefes Arch Clin Exp Ophthalmol. 1994 Jun;232(6):361-7. doi: 10.1007/BF00175988.
10
Prolonged rod dark adaptation in retinitis pigmentosa.视网膜色素变性中的长时间视杆细胞暗适应
Br J Ophthalmol. 1984 Aug;68(8):561-9. doi: 10.1136/bjo.68.8.561.