Kusser W, Pisabarro A G, De Pedro M A, Ishiguro E E
Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
Antimicrob Agents Chemother. 1990 Jan;34(1):164-6. doi: 10.1128/AAC.34.1.164.
The ability to induce the ampicillin-mediated lysis of amino acid-deprived Escherichia coli by relaxing the stringent response decreased progressively during the course of amino acid deprivation, apparently because of a time-dependent decay in a key lysis event. The decay of this labile activity was not apparent when ampicillin treatment was initiated early and maintained continuously throughout the amino acid starvation period.
通过放松严紧反应来诱导氨苄青霉素介导的氨基酸饥饿型大肠杆菌裂解的能力，在氨基酸饥饿过程中逐渐下降，这显然是由于关键裂解事件中存在时间依赖性的衰减。当在氨基酸饥饿期早期开始氨苄青霉素处理并持续维持时，这种不稳定活性的衰减并不明显。
