• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

轴向骨骼中的良性脊索瘤病变:综述及最新评价。

Benign notochordal lesions of the axial skeleton: a review and current appraisal.

机构信息

Division of Surgical Pathology, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

Skeletal Radiol. 2011 Sep;40(9):1141-52. doi: 10.1007/s00256-011-1167-6. Epub 2011 Aug 17.

DOI:10.1007/s00256-011-1167-6
PMID:21847746
Abstract

At the 1996 meeting of the International Skeletal Society, an idea was put forth that there existed symptomatic lesions of the axial skeleton, morphologically different from chordoma, that were consistent with benign notochordal remnants (rests). A review of the embryological basis for this concept is made, along with an analysis of these lesions, termed giant notochordal rests or benign notochordal cell tumors, that have been reported in the intervening 15 years, with a commentary on their relationship, if any, to chordoma.

摘要

在 1996 年国际骨骼协会会议上,提出了一个观点,即存在与脊索瘤形态不同的轴向骨骼症状性病变,这些病变与良性脊索残余(遗迹)一致。本文回顾了这一概念的胚胎学基础,并对这些病变进行了分析,这些病变被称为巨大脊索遗迹或良性脊索细胞肿瘤,在过去的 15 年中已有报道,并对其与脊索瘤的关系进行了评论,如果有的话。

相似文献

1
Benign notochordal lesions of the axial skeleton: a review and current appraisal.轴向骨骼中的良性脊索瘤病变:综述及最新评价。
Skeletal Radiol. 2011 Sep;40(9):1141-52. doi: 10.1007/s00256-011-1167-6. Epub 2011 Aug 17.
2
Intraosseous benign notochordal cell tumor.骨内良性脊索细胞肿瘤。
Arch Pathol Lab Med. 2010 Feb;134(2):283-8. doi: 10.5858/134.2.283.
3
The surgical pathology of notochordal remnants in adult intervertebral disks: a report of 3 cases.成人椎间盘脊索残余的外科病理学:3例报告
Am J Surg Pathol. 2008 Aug;32(8):1123-9. doi: 10.1097/PAS.0b013e3181757954.
4
Benign notochordal cell tumors of the spine: natural history of 8 patients with histologically confirmed lesions.脊柱良性脊索细胞肿瘤:8 例组织学证实病变患者的自然病史。
Neurosurgery. 2013 Sep;73(3):411-6. doi: 10.1227/01.neu.0000431476.94783.c6.
5
Incipient chordoma: a report of two cases of early-stage chordoma arising from benign notochordal cell tumors.早期脊索瘤:两例起源于良性脊索细胞肿瘤的早期脊索瘤病例报告。
Mod Pathol. 2005 Jul;18(7):1005-10. doi: 10.1038/modpathol.3800378.
6
Lumbar vertebral chordoma arising from an intraosseous benign notochordal cell tumour: radiological findings and histopathological description with a good clinical outcome.源自骨内良性脊索瘤细胞肿瘤的腰椎脊索瘤:影像学表现和组织病理学描述,临床预后良好。
Br J Radiol. 2010 Mar;83(987):e49-53. doi: 10.1259/bjr/63846600.
7
Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3.经典脊索瘤与良性脊索细胞残余并存,表现出不同的 brachyury 和半乳糖凝集素-3 的免疫组织化学表达模式。
J Clin Neurosci. 2011 Jan;18(1):96-9. doi: 10.1016/j.jocn.2010.03.066. Epub 2010 Sep 19.
8
Intraosseous benign notochord cell tumors (BNCT): further evidence supporting a relationship to chordoma.骨内良性脊索细胞瘤(BNCT):支持与脊索瘤存在关联的进一步证据。
Am J Surg Pathol. 2007 Oct;31(10):1573-7. doi: 10.1097/PAS.0b013e31805c9967.
9
Giant vertebral notochordal rest: magnetic resonance and diffusion weighted imaging findings.巨大的椎体脊索残余:磁共振成像和扩散加权成像表现
Korean J Radiol. 2009 May-Jun;10(3):303-6. doi: 10.3348/kjr.2009.10.3.303. Epub 2009 Apr 22.
10
First histologically confirmed case of a classic chordoma arising in a precursor benign notochordal lesion: differential diagnosis of benign and malignant notochordal lesions.首例经组织学确诊的起源于良性脊索前体病变的经典脊索瘤:良性与恶性脊索病变的鉴别诊断
Skeletal Radiol. 2002 Jul;31(7):413-8. doi: 10.1007/s00256-002-0514-z. Epub 2002 May 15.

引用本文的文献

1
Case Report: Multiple primary bilateral lung benign notochord cell tumors combined with sacral tumors.病例报告:多发性原发性双侧肺良性脊索细胞瘤合并骶骨肿瘤。
Front Oncol. 2025 May 21;15:1537943. doi: 10.3389/fonc.2025.1537943. eCollection 2025.
2
Primary Benign Neoplasms of the Spine.脊柱原发性良性肿瘤
Diagnostics (Basel). 2023 Jun 8;13(12):2006. doi: 10.3390/diagnostics13122006.
3
Chordomas: Histopathological Study in View of Anatomical Location.脊索瘤:基于解剖部位的组织病理学研究。

本文引用的文献

1
ECCHORDOSIS PHYSALIPHORA SPHENO-OCCIPITALIS.蝶枕部泡状脊索瘤
J Neurol Psychopathol. 1923 Nov;4(15):218-20. doi: 10.1136/jnnp.s1-4.15.218.
2
Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3.经典脊索瘤与良性脊索细胞残余并存,表现出不同的 brachyury 和半乳糖凝集素-3 的免疫组织化学表达模式。
J Clin Neurosci. 2011 Jan;18(1):96-9. doi: 10.1016/j.jocn.2010.03.066. Epub 2010 Sep 19.
3
Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases.
J Korean Med Sci. 2019 Apr 8;34(13):e107. doi: 10.3346/jkms.2019.34.e107.
4
Computed tomography and magnetic resonance imaging features of cervical chordoma.颈椎脊索瘤的计算机断层扫描和磁共振成像特征
Oncol Lett. 2018 Jul;16(1):861-865. doi: 10.3892/ol.2018.8721. Epub 2018 May 16.
5
State-of-the-Art Imaging in Human Chordoma of the Skull Base.颅底脊索瘤的最新成像技术
Curr Radiol Rep. 2018;6(5):16. doi: 10.1007/s40134-018-0275-7. Epub 2018 Apr 3.
6
[Updates to the WHO classification of bone tumours].[世界卫生组织骨肿瘤分类的更新]
Pathologe. 2018 Mar;39(2):107-116. doi: 10.1007/s00292-017-0396-4.
7
[Notochordal tumors : Benign notochordal tumors and chordomas].[脊索瘤:良性脊索瘤和脊膜瘤]
Pathologe. 2018 Mar;39(2):117-124. doi: 10.1007/s00292-017-0399-1.
8
Chordoma arising from benign multifocal notochordal tumors.脊索瘤起源于良性多灶性脊索瘤肿瘤。
Skeletal Radiol. 2017 Dec;46(12):1745-1752. doi: 10.1007/s00256-017-2727-1. Epub 2017 Aug 3.
9
SMD Kozlowski type caused by p.Arg594His substitution in TRPV4 reveals abnormal ossification and notochordal remnants in discs and vertebrae.由TRPV4基因中p.Arg594His替换导致的科兹洛夫斯基型SMD揭示了椎间盘和椎体中的异常骨化和脊索残余。
Eur J Med Genet. 2017 Oct;60(10):509-516. doi: 10.1016/j.ejmg.2017.07.004. Epub 2017 Jul 4.
10
Difficulty distinguishing benign notochordal cell tumor from chordoma further suggests a link between them.难以区分良性脊索细胞瘤与脊索瘤这一情况进一步表明了它们之间的联系。
Cancer Imaging. 2014 Apr 22;14(1):4. doi: 10.1186/1470-7330-14-4.
重新审视具有 brachyury 的脊索瘤:一项针对 51 例的验证研究分析。
Arch Pathol Lab Med. 2010 Aug;134(8):1181-7. doi: 10.5858/2009-0476-OA.1.
4
Intraosseous benign notochordal cell tumor.骨内良性脊索细胞肿瘤。
Arch Pathol Lab Med. 2010 Feb;134(2):283-8. doi: 10.5858/134.2.283.
5
Teratoma of the ovary, with a segment of vertebral column and remnants of notochordal tissue: Report of a case.卵巢畸胎瘤,伴有一段脊柱和脊索组织残余:病例报告
Am J Pathol. 1940 Sep;16(5):625-634.5.
6
A rare case of intraosseous benign notochordal cell tumor of the coccyx.1例罕见的尾骨骨内良性脊索细胞瘤。
Orthopedics. 2009 Jun;32(6):445. doi: 10.3928/01477447-20090511-22.
7
Giant vertebral notochordal rest: magnetic resonance and diffusion weighted imaging findings.巨大的椎体脊索残余:磁共振成像和扩散加权成像表现
Korean J Radiol. 2009 May-Jun;10(3):303-6. doi: 10.3348/kjr.2009.10.3.303. Epub 2009 Apr 22.
8
The surgical pathology of notochordal remnants in adult intervertebral disks: a report of 3 cases.成人椎间盘脊索残余的外科病理学:3例报告
Am J Surg Pathol. 2008 Aug;32(8):1123-9. doi: 10.1097/PAS.0b013e3181757954.
9
Distinguishing benign notochordal cell tumors from vertebral chordoma.鉴别良性脊索细胞瘤与椎体脊索瘤。
Skeletal Radiol. 2008 Apr;37(4):291-9. doi: 10.1007/s00256-007-0435-y. Epub 2008 Jan 8.
10
Notochordal inclusions in the vertebral bone marrow.椎骨骨髓中的脊索包涵体。
J Bone Miner Res. 2008 Apr;23(4):572-5. doi: 10.1359/jbmr.071204.