Department of Neuroscience and Pharmacology, Laboratory for Motor Control, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
Med Eng Phys. 2012 Mar;34(2):219-24. doi: 10.1016/j.medengphy.2011.07.013. Epub 2011 Aug 17.
Previous investigations have suggested considerable inter-individual variability in the time course pattern of net joint moments during normal human walking, although the limited sample sizes precluded statistical analyses. The purpose of the present study was to obtain joint moment patterns from a group of normal subjects and to test whether or not the expected differences would prove to be statistically significant. Fifteen healthy male subjects were recorded on video while they walked across two force platforms. Ten kinematic and kinetic parameters were selected and input to a statistical cluster analysis to determine whether or not the 15 subjects could be divided into different 'families' (clusters) of walking strategy. The net joint moments showed a variability corroborating earlier reports. The cluster analysis showed that the 15 subjects could be grouped into two clusters of 5 and 10 subjects, respectively. Five parameters differed significantly, so the group of 5 subjects was characterized by (1) a higher peak knee joint extensor moment, (2) more flexed knee joint angle at heel strike, (3) during the whole stance phase, (4) lower peak knee joint flexor moment and (5) lower ankle joint angle at flat foot position. Calculation of bone-on-bone forces in the knee joint showed a value of 64 N/kg body weight in the K+ group and 55 N/kg in the K- group (p<0.05). It is unknown if differences of similar magnitude contribute to early joint degeneration in some individuals while not in others.
先前的研究表明,在正常人行走过程中,净关节力矩的时间历程模式存在相当大的个体间变异性,尽管样本量有限,无法进行统计分析。本研究的目的是从一组正常受试者中获得关节力矩模式,并检验预期的差异是否具有统计学意义。15 名健康男性受试者在穿过两个力台时被录像记录。选择了 10 个运动学和动力学参数,并输入到统计聚类分析中,以确定 15 名受试者是否可以分为不同的行走策略“家族”(聚类)。净关节力矩显示出与早期报告一致的变异性。聚类分析表明,15 名受试者可以分为两组,每组 5 名和 10 名受试者。有 5 个参数差异显著,因此,5 名受试者的特征为:(1)膝关节伸肌峰值力矩较高,(2)在足跟触地时膝关节角度更弯曲,(3)在整个站立阶段,(4)膝关节屈肌峰值力矩较低,(5)平足位置时踝关节角度较低。膝关节的骨对骨力的计算显示,K+组的数值为 64 N/kg 体重,K-组为 55 N/kg(p<0.05)。目前尚不清楚类似大小的差异是否会导致某些人早期关节退化,而其他人则不会。