Division of Neurology/Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Epilepsy Res. 2012 Jul;100(3):261-6. doi: 10.1016/j.eplepsyres.2011.05.020. Epub 2011 Aug 19.
The ketogenic diet (KD) is an effective treatment for epilepsy and like other treatments it is not without side effects. The side effects encountered are related to the diet composition and the radical metabolic changes that results from a high fat, low carbohydrate and protein diet. Short-term side effects are well documented. Long-term side effects are not as well documented but since the last "international symposium on dietary therapies for epilepsy and other neurological disorders", there are now more prospective and longitudinal data. Monitoring practices and treatments will be discussed and compared to the International Ketogenic Diet Consensus Statement (IKDCS) from 2008.
生酮饮食(KD)是一种有效的癫痫治疗方法,与其他治疗方法一样,它也并非没有副作用。所遇到的副作用与饮食成分以及高脂肪、低碳水化合物和低蛋白质饮食导致的激进代谢变化有关。短期副作用已有详细记录。长期副作用则没有那么详细的记录,但自上次“关于癫痫和其他神经障碍的饮食治疗国际研讨会”以来,现在有了更多的前瞻性和纵向数据。本文将讨论监测实践和治疗,并将其与 2008 年的国际生酮饮食共识声明(IKDCS)进行比较。