Division of Intensive Care Medicine, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
Cardiol Res Pract. 2012;2012:407035. doi: 10.1155/2012/407035. Epub 2011 Aug 11.
Acute lung injury carries a high burden of morbidity and mortality and is characterised by nonhydrostatic pulmonary oedema. The aim of this paper is to highlight the role of accurate quantification of extravascular lung water in diagnosis, management, and prognosis in "acute lung injury" and "acute respiratory distress syndrome". Several studies have verified the accuracy of both the single and the double transpulmonary thermal indicator techniques. Both experimental and clinical studies were searched in PUBMED using the term "extravascular lung water" and "acute lung injury". Extravascular lung water measurement offers information not otherwise available by other methods such as chest radiography, arterial blood gas, and chest auscultation at the bedside. Recent data have highlighted the role of extravascular lung water in response to treatment to guide fluid therapy and ventilator strategies. The quantification of extravascular lung water may predict mortality and multiorgan dysfunction. The limitations of the dilution method are also discussed.
急性肺损伤具有高发病率和死亡率，其特征为非静水肺水肿。本文旨在强调准确量化肺外水在“急性肺损伤”和“急性呼吸窘迫综合征”中的诊断、管理和预后中的作用。多项研究已经验证了单指示剂和双指示剂经肺温度稀释技术的准确性。使用“肺外水”和“急性肺损伤”这两个术语在 PUBMED 中搜索了实验和临床研究。肺外水测量提供了其他方法（如床边胸部 X 线、动脉血气和胸部听诊）无法提供的信息。最近的数据强调了肺外水在治疗反应中的作用，以指导液体治疗和呼吸机策略。肺外水的量化可以预测死亡率和多器官功能障碍。还讨论了稀释法的局限性。
