State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, P R China.
Parasit Vectors. 2011 Aug 24;4:165. doi: 10.1186/1756-3305-4-165.
Toxoplasmosis is a zoonotic infection of humans and animals, caused by the opportunistic protozoan Toxoplasma gondii, a parasite belonging to the phylum Apicomplexa. Infection in pregnant women may lead to abortion, stillbirth or other serious consequences in newborns. Infection in immunocompromised patients can be fatal if not treated. On average, one third of people are chronically infected worldwide. Although very limited information from China has been published in the English journals, T. gondii infection is actually a significant human health problem in China. In the present article, we reviewed the clinical features, transmission, prevalence of T. gondii infection in humans in China, and summarized genetic characterizations of reported T. gondii isolates. Educating the public about the risks associated with unhealthy food and life style habits, tracking serological examinations to special populations, and measures to strengthen food and occupational safety are discussed.
弓形虫病是一种人兽共患的感染病，由机会性病原体刚地弓形虫引起，这是一种属于顶复门的寄生虫。孕妇感染可能导致流产、死产或新生儿其他严重后果。免疫功能低下患者的感染如不治疗可能致命。全球平均有三分之一的人受到慢性感染。尽管中国在英文期刊上发表的相关信息非常有限，但实际上弓形虫感染在中国是一个严重的人类健康问题。在本文中，我们综述了中国弓形虫感染的临床特征、传播途径、人群感染流行情况，并总结了报道的弓形虫分离株的遗传特征。讨论了针对不良饮食和生活习惯相关风险的公众教育、对特殊人群的血清学检测跟踪，以及加强食品和职业安全的措施。
