Intelligent Systems Research Centre, School of Computing and Intelligent Systems, University of Ulster, Magee Campus, Londonderry BT487JL, Northern Ireland, UK.
Neuroimage. 2012 Jan 16;59(2):1795-803. doi: 10.1016/j.neuroimage.2011.08.010. Epub 2011 Aug 16.
This study sought to investigate the effects of manipulating social coordination on brain synchronization/de-synchronization in the mu band. Mu activation is associated with understanding and coordinating motor acts and may play a key role in mediating social interaction. Members of a dyad were required to interact with one another in a rhythmic finger movement coordination task under various instructions: intrinsic where each member of the dyad was instructed to maintain their own and ignore their partner's movement; in-phase where they were asked to synchronize with their partner's movement; and anti-phase where they were instructed to syncopate with their partner's movement. EEG and movement data were recorded simultaneously from both subjects during all three tasks and a control condition. Log power ratios of EEG activity in the active conditions versus control were used to assess the effect of task context on synchronization/de-synchronization in the mu spectral domain. Results showed clear and systematic modulation of mu band activity in the 10-12 Hz range as a function of coordination context. In the left hemisphere general levels of alpha-mu suppression increased progressively as one moved from intrinsic through in-phase to anti-phase contexts but with no specific central-parietal focus. In contrast the right hemisphere displayed context-specific changes in the central-parietal region. The intrinsic condition showed a right synchronization which disappeared with the in-phase context even as de-synchronization remained greater in the left hemisphere. Anti-phase was associated with larger mu suppression in the right in comparison with left at central-parietal region. Such asymmetrical changes were highly correlated with changing behavioral dynamics. These specific patterns of activation and deactivation of mu activity suggest that localized neural circuitry in right central-parietal regions mediates how individuals interpret the movements of others in the context of their own actions. A right sided mechanism in the 10-12 Hz range appears to be involved in integrating the mutual information among the members of a dyad that enables the dynamics of social interaction to unfold in time.
本研究旨在探讨在 mu 频段操纵社会协调对大脑同步/去同步的影响。mu 激活与理解和协调运动行为有关，可能在调节社会互动方面发挥关键作用。在各种指令下，要求二联体的成员在节奏性手指运动协调任务中相互作用：内在的，每个二联体成员都被指示保持自己的运动并忽略他们伙伴的运动；同相的，他们被要求与他们伙伴的运动同步；反相的，他们被指示与他们伙伴的运动错开。在所有三个任务和一个对照条件下，同时从两个主体记录 EEG 和运动数据。活动条件下的 EEG 活动对数功率比用于评估任务上下文对 mu 光谱域同步/去同步的影响。结果表明，作为协调上下文的函数，mu 频段活动在 10-12 Hz 范围内出现明显而系统的调制。在左半球，随着从内在到同相再到反相的转变，alpha-mu 抑制的总体水平逐渐增加，但没有特定的中央顶叶焦点。相比之下，右半球显示出中央顶叶区域的上下文特异性变化。内在条件显示出右侧同步，即使在同相条件下，这种同步也消失了，而左半球的去同步仍然更大。与左半球相比，反相在中央顶叶区域与更大的 mu 抑制相关。这种不对称变化与不断变化的行为动力学高度相关。这种 mu 活动的激活和去激活的特定模式表明，右中央顶叶区域的局部神经回路介导了个体如何在自己的动作背景下解释他人的动作。在 10-12 Hz 范围内的右侧机制似乎参与了整合二联体成员之间的互信息，从而使社会互动的动态能够随时间展开。
