通过按蚊控制疟原虫传播的高低技术方法。
Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes.
机构信息
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
出版信息
J Trop Med. 2011;2011:891342. doi: 10.1155/2011/891342. Epub 2011 Aug 17.
Abstract
Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.
摘要
目前的努力已经证明不足以阻止疟原虫寄生虫通过按蚊传播，因此急需一套新的策略来抑制疟原虫对蚊子的感染。在本文中，我们总结了两种疟疾控制方法的研究，一种是基于利用蚊子天然菌群抑制寄生虫的低技术策略，另一种是利用遗传修饰使蚊子具有抗感染力的高技术策略，并讨论了这两种方法的优缺点。
相似文献
1
Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes.通过按蚊控制疟原虫传播的高低技术方法。
J Trop Med. 2011;2011:891342. doi: 10.1155/2011/891342. Epub 2011 Aug 17.
2
A natural Anopheles-associated Penicillium chrysogenum enhances mosquito susceptibility to Plasmodium infection.一种与按蚊自然相关的产黄青霉增强了蚊子对疟原虫感染的易感性。
Sci Rep. 2016 Sep 28;6:34084. doi: 10.1038/srep34084.
3
Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence.对影响媒介能力的肠杆菌、按蚊和疟原虫相互作用进行的功能基因组分析。
Malar J. 2016 Aug 22;15(1):425. doi: 10.1186/s12936-016-1468-2.
4
Implication of the mosquito midgut microbiota in the defense against malaria parasites.蚊子中肠微生物群在抵御疟原虫中的作用。
PLoS Pathog. 2009 May;5(5):e1000423. doi: 10.1371/journal.ppat.1000423. Epub 2009 May 8.
5
Last-come, best served? Mosquito biting order and transmission.最后来的，服务最好？蚊子叮咬顺序和传播。
Proc Biol Sci. 2020 Nov 25;287(1939):20202615. doi: 10.1098/rspb.2020.2615.
6
Immune Regulation of Is Species Specific and Infection Intensity Dependent.免疫调节的 是 种特异性和感染强度依赖性的。
mBio. 2017 Oct 17;8(5):e01631-17. doi: 10.1128/mBio.01631-17.
7
The Anopheles FBN9 immune factor mediates Plasmodium species-specific defense through transgenic fat body expression.按蚊FBN9免疫因子通过转基因脂肪体表达介导疟原虫物种特异性防御。
Dev Comp Immunol. 2017 Feb;67:257-265. doi: 10.1016/j.dci.2016.09.012. Epub 2016 Sep 22.
8
When Is a Plasmodium-Infected Mosquito an Infectious Mosquito?当疟原虫感染的蚊子成为传染性蚊子时？
Trends Parasitol. 2020 Aug;36(8):705-716. doi: 10.1016/j.pt.2020.05.011. Epub 2020 Jul 1.
9
Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission.暴露于抗疟药物的按蚊会阻止疟原虫寄生虫的传播。
Nature. 2019 Mar;567(7747):239-243. doi: 10.1038/s41586-019-0973-1. Epub 2019 Feb 27.
10
Do mosquitoes transmit the avian malaria-like parasite Haemoproteus? An experimental test of vector competence using mosquito saliva.蚊子会传播类似禽疟的寄生虫血变原虫吗？一项使用蚊子唾液进行媒介能力的实验测试。
Parasit Vectors. 2016 Nov 28;9(1):609. doi: 10.1186/s13071-016-1903-9.
引用本文的文献
1
Composition and structure of the culturable gut bacterial communities in Anopheles albimanus from Colombia.哥伦比亚致倦库蚊肠道可培养细菌群落的组成与结构。
PLoS One. 2019 Dec 2;14(12):e0225833. doi: 10.1371/journal.pone.0225833. eCollection 2019.
2
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection.一种真菌病原体分泌一种小的沉默 RNA，削弱蚊子的免疫力并促进感染。
Nat Commun. 2019 Sep 20;10(1):4298. doi: 10.1038/s41467-019-12323-1.
3
Influence of midgut microbiota in Anopheles stephensi on Plasmodium berghei infections.按蚊中肠微生物群对伯氏疟原虫感染的影响。
Malar J. 2018 Oct 25;17(1):385. doi: 10.1186/s12936-018-2535-7.
4
Priorities for Broadening the Malaria Vector Control Tool Kit.扩大疟疾媒介控制工具包的优先事项。
Trends Parasitol. 2017 Oct;33(10):763-774. doi: 10.1016/j.pt.2017.06.003. Epub 2017 Jun 28.
5
Role of NF-kβ factor Rel2 during Plasmodium falciparum and bacterial infection in Anopheles dirus.NF-kβ因子Rel2在大劣按蚊感染恶性疟原虫和细菌过程中的作用
Parasit Vectors. 2016 Sep 29;9(1):525. doi: 10.1186/s13071-016-1810-0.
6
Molecular characterization of midgut microbiota of Aedes albopictus and Aedes aegypti from Arunachal Pradesh, India.印度阿鲁纳恰尔邦白纹伊蚊和埃及伊蚊中肠微生物群的分子特征
Parasit Vectors. 2015 Dec 18;8:641. doi: 10.1186/s13071-015-1252-0.
7
Chromobacterium Csp_P reduces malaria and dengue infection in vector mosquitoes and has entomopathogenic and in vitro anti-pathogen activities.嗜麦芽窄食单胞菌Csp_P可降低媒介蚊子感染疟疾和登革热的几率，并具有昆虫致病性和体外抗病原体活性。
PLoS Pathog. 2014 Oct 23;10(10):e1004398. doi: 10.1371/journal.ppat.1004398. eCollection 2014 Oct.
8
Innexin AGAP001476 is critical for mediating anti-Plasmodium responses in Anopheles mosquitoes.Innexin AGAP001476 对介导按蚊抗疟原虫反应至关重要。
J Biol Chem. 2014 Sep 5;289(36):24885-97. doi: 10.1074/jbc.M114.554519. Epub 2014 Jul 17.
9
Exploring Anopheles gut bacteria for Plasmodium blocking activity.探索按蚊肠道细菌的疟原虫阻断活性。
Environ Microbiol. 2014 Sep;16(9):2980-94. doi: 10.1111/1462-2920.12381. Epub 2014 Feb 24.
10
The Anopheles innate immune system in the defense against malaria infection.按蚊的先天免疫系统在抵御疟疾感染中的作用。
J Innate Immun. 2014;6(2):169-81. doi: 10.1159/000353602. Epub 2013 Aug 28.
本文引用的文献
1
Natural microbe-mediated refractoriness to Plasmodium infection in Anopheles gambiae.自然微生物介导的冈比亚按蚊对疟原虫感染的抵抗力。
Science. 2011 May 13;332(6031):855-8. doi: 10.1126/science.1201618.
2
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito.基于合成归巢内切酶的基因驱动系统在人类疟疾蚊中的应用。
Nature. 2011 May 12;473(7346):212-5. doi: 10.1038/nature09937. Epub 2011 Apr 20.
3
Genetic elimination of dengue vector mosquitoes.遗传消除登革热媒介蚊。
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4772-5. doi: 10.1073/pnas.1019295108. Epub 2011 Mar 7.
4
Development of Metarhizium anisopliae and Beauveria bassiana formulations for control of malaria mosquito larvae.开发金龟子绿僵菌和球孢白僵菌制剂以控制疟蚊幼虫。
Parasit Vectors. 2011 Feb 22;4:23. doi: 10.1186/1756-3305-4-23.
5
Analysis of two novel midgut-specific promoters driving transgene expression in Anopheles stephensi mosquitoes.分析两种新型中肠特异性启动子在斯氏按蚊中转基因表达。
PLoS One. 2011 Feb 4;6(2):e16471. doi: 10.1371/journal.pone.0016471.
6
Site-specific integration and expression of an anti-malarial gene in transgenic Anopheles gambiae significantly reduces Plasmodium infections.转基因冈比亚按蚊中抗疟基因的特异性整合和表达显著降低了疟原虫感染。
PLoS One. 2011 Jan 25;6(1):e14587. doi: 10.1371/journal.pone.0014587.
7
Persistence of Bacillus thuringiensis israelensis (Bti) in the environment induces resistance to multiple Bti toxins in mosquitoes.苏云金芽孢杆菌以色列亚种（Bti）在环境中的持续存在会导致蚊子对多种 Bti 毒素产生抗性。
Pest Manag Sci. 2011 Jan;67(1):122-8. doi: 10.1002/ps.2046. Epub 2010 Oct 27.
8
Science and society. GM mosquito trial alarms opponents, strains ties in Gates-funded project.科学与社会。转基因蚊子试验引发反对者警觉，盖茨资助项目的关系紧张。
Science. 2010 Nov 19;330(6007):1030-1. doi: 10.1126/science.330.6007.1030.
9
The Cartagena Protocol and genetically modified mosquitoes.《卡塔赫纳议定书》与转基因蚊子
Nat Biotechnol. 2010 Sep;28(9):896-7. doi: 10.1038/nbt0910-896.
10
Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes.激活 Akt 信号通路可降低斯氏按蚊感染疟原虫的发生率和感染强度，并缩短其寿命。
PLoS Pathog. 2010 Jul 15;6(7):e1001003. doi: 10.1371/journal.ppat.1001003.
Zotero 插件