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巴西钩端螺旋体分离株多位点序列分型分析。

Analysis of multilocus sequence typing for identification of Leptospira isolates in Brazil.

机构信息

Center of Bacteriology, Adolfo Lutz Institute, São Paulo, SP, Brazil.

出版信息

J Clin Microbiol. 2011 Nov;49(11):3940-2. doi: 10.1128/JCM.01119-11. Epub 2011 Aug 31.

DOI:10.1128/JCM.01119-11
PMID:21880969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209071/
Abstract

A collection of 101 Leptospira isolates was tested by multilocus sequence typing (MLST) and by traditional serotyping. MLST divided the isolates into 4 sequence types (STs), while serotyping classified them into 6 serogroups. Two isolates failed to generate products for some genes by MLST. MLST was less discriminatory than serotyping for uncommonly occurring isolates from humans in Brazil.

摘要

收集了 101 株钩端螺旋体分离株，通过多位点序列分型（MLST）和传统血清分型进行了测试。MLST 将分离株分为 4 种序列型（ST），而血清分型将它们分为 6 个血清群。有两个分离株的某些基因 MLST 无法产生产物。对于在巴西从人类中分离出的罕见分离株，MLST 的分辨力不如血清分型。