Harrison Kelly A, Robertson Sheilah A, Levy Julie K, Isaza Natalie M
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0136, USA.
J Feline Med Surg. 2011 Dec;13(12):896-902. doi: 10.1016/j.jfms.2011.06.010. Epub 2011 Aug 31.
A combination of medetomidine (M, 100 μg/kg), ketamine (K, 10 mg/kg) and buprenorphine (B, 10 μg/kg), administered by intramuscular injection, was evaluated for spaying and castration (neutering) of feral cats (n = 101). Eleven animals (11%) required supplemental anesthesia (isoflurane by mask) to maintain an adequate plane of surgical anesthesia. Atipamezole (A, 125 μg/kg) was administered subcutaneously at the completion of surgery. All cats recovered from surgery and were released the following day. A hemoglobin saturation (SpO(2)) value of < 95% was recorded at least once during anesthesia in all cats. This MKB combination can be used in a feral cat sterilization clinic, but isoflurane supplementation may be necessary. Further research is indicated to determine the clinical significance of the low SpO(2) values associated with this anesthetic regimen.
通过肌肉注射给予美托咪定（M，100μg/kg）、氯胺酮（K，10mg/kg）和丁丙诺啡（B，10μg/kg）的组合，对101只野猫进行绝育手术（去势）评估。11只动物（11%）需要补充麻醉（面罩吸入异氟烷）以维持足够的手术麻醉平面。手术结束时皮下注射阿替美唑（A，125μg/kg）。所有猫均从手术中恢复，并于次日放生。所有猫在麻醉期间至少有一次血红蛋白饱和度（SpO₂）值记录低于95%。这种MKB组合可用于野猫绝育诊所，但可能需要补充异氟烷。建议进一步研究以确定与这种麻醉方案相关的低SpO₂值的临床意义。
