Laktasić-Zerjavić Nadica, Korsić Mirko, Crncević-Orlić Zeljka, Anić Branimir
Klinika za reumatske bolesti i rehabilitaciju, KBC Zagreb.
Lijec Vjesn. 2011 May-Jun;133(5-6):194-204.
In the last decade there has been a rising recognition of potential clinical significance of the vitamin D. Vitamin D regulates about 3% of the human genome. Thus, vitamin D deficiency is common and high in various populations across the world including Croatia. In this paper vitamin D metabolism and up to date knowledge of vitamin D function in calcium metabolism, muscular function and in prevention of infection, malignancy, autoimmune and cardiovascular diseases is presented. Reasons for pandemic vitamin D deficiency and guidelines for vitamin D supplementation are given.
在过去十年中，人们对维生素D潜在的临床意义的认识不断提高。维生素D调节约3%的人类基因组。因此，维生素D缺乏在世界各地的不同人群中都很常见且比例很高，包括克罗地亚。本文介绍了维生素D的代谢以及关于其在钙代谢、肌肉功能以及预防感染、恶性肿瘤、自身免疫性疾病和心血管疾病方面功能的最新知识。文中给出了维生素D缺乏大流行的原因以及维生素D补充的指南。
