Department of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, Washington, USA.
mBio. 2011 Sep 6;2(5). doi: 10.1128/mBio.00141-11. Print 2011.
Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.
活性氧（ROS）由宿主吞噬细胞产生，并对广泛的病原体发挥抗菌作用。ROS 的可观察到的抗菌作用高度依赖于实验条件。本观点综述了最近关于沙门氏菌-吞噬细胞相互作用中 ROS 的争议，并试图调和来自不同实验室的相互矛盾的观察结果。
