钌（II）多吡啶配合物作为 DNA 载体。
Ruthenium(II) polypyridyl complexes as carriers for DNA delivery.
机构信息
Department of Chemistry, University of Pune, Pune- 411007, India.
出版信息
Chem Commun (Camb). 2011 Oct 21;47(39):11068-70. doi: 10.1039/c1cc13863d. Epub 2011 Sep 6.
PMID:21897939
Abstract
Two novel water soluble ruthenium(II) complexes Ru(bpy)(2)(bqbg) and Ru(phen)(2)(bqbg) have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated.
摘要
两种新型水溶性钌（II）配合物Ru(bpy)(2)(bqbg)和Ru(phen)(2)(bqbg)已被结构表征，并评估了它们作为潜在非病毒 DNA 载体的 DNA 凝聚活性、细胞毒性和 DNA 凝聚物的细胞摄取研究。
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