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一些商业精油及其主要化合物的抗氧化和抗乙酰胆碱酯酶活性。

Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds.

机构信息

Laboratory of Physiology-Pharmacology-Environmental Health, Faculty of Sciences Dhar El Mehraz, BP 1796 Atlas, University Sidi Mohamed Ben Abdallah, Fez 30 000, Morocco.

出版信息

Molecules. 2011 Sep 7;16(9):7672-90. doi: 10.3390/molecules16097672.

DOI:10.3390/molecules16097672
PMID:21900869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6264425/
Abstract

The commercial essential oils of Citrus aurantium L., Cupressus sempervirens L., Eucalyptus globulus Labill., Foeniculum vulgare Mill. and Thymus vulgaris L., isolated by steam distillation by a company of Morocco were evaluated in terms of in vitro antioxidant activity through several methods. In vitro acetylcholinesterase inhibitory activity was also determined. Citrus limon (L.) Burm. f. oil was also studied, but it was obtained by peel expression. The best antioxidant was T. vulgaris oil, independent of the method used, mainly due to the presence of the phenolic monoterpenes thymol and carvacrol, which when studied as single compounds also presented the best activities. Concerning the acetylcholinesterase inhibition activity, E. globulus was the most effective. Nevertheless its main components 1,8-cineole and limonene were not the most active, a feature that corresponded to d-3-carene.

摘要

由摩洛哥的一家公司通过水蒸气蒸馏法分别提取的甜橙(Citrus aurantium L.)、柏木(Cupressus sempervirens L.)、蓝桉(Eucalyptus globulus Labill.)、小茴香(Foeniculum vulgare Mill.)和普通百里香(Thymus vulgaris L.)的商业精油,通过几种方法评估了其体外抗氧化活性。还测定了体外乙酰胆碱酯酶抑制活性。柠檬(Citrus limon (L.)Burm. f.)油也进行了研究,但它是通过果皮表达获得的。最好的抗氧化剂是普通百里香油,无论使用哪种方法,这主要是由于存在酚类单萜香芹酚和香茅醇,当作为单一化合物进行研究时,它们也表现出最好的活性。关于乙酰胆碱酯酶抑制活性,蓝桉最有效。然而,其主要成分 1,8-桉叶素和柠檬烯并不是最活跃的,这一特点与 d-3-蒈烯相对应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/a172dbfd2b8c/molecules-16-07672-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/414ed2f4216a/molecules-16-07672-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/8fe8efdf2961/molecules-16-07672-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/7a8011c70996/molecules-16-07672-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/a172dbfd2b8c/molecules-16-07672-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/414ed2f4216a/molecules-16-07672-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/8fe8efdf2961/molecules-16-07672-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/7a8011c70996/molecules-16-07672-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49ad/6264425/a172dbfd2b8c/molecules-16-07672-g004.jpg

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