Foxcroft David R, Tsertsvadze Alexander
School of Health and Social Care, Oxford Brookes University, Marston Road, Jack Straws Lane, Marston, Oxford, England, UK, OX3 0FL.
Cochrane Database Syst Rev. 2011 Sep 7(9):CD009308. doi: 10.1002/14651858.CD009308.
Alcohol misuse in young people is a cause of concern for health services, policy makers, prevention workers, and criminal justice system, youth workers, teachers, and parents.
To systematically review evidence on the effectiveness of universal family-based prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age. To update a part of a previously published Cochrane systematic review.
Relevant evidence (up to 2002) was selected from the previous Cochrane review. Later studies, to July 2010, were identified from MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, Project CORK, and PsycINFO.
Randomized trials evaluating universal family-based prevention programs and reporting outcomes for alcohol use in students 18 years of age or younger were included. Two reviewers screened titles/abstracts and full text of identified records.
Two reviewers extracted relevant data independently using an a priori defined extraction form. Risk of bias was assessed.
12 parallel-group trials were included. The reporting quality of trials was poor, only 20% of them reporting adequate method of randomisation and program allocation concealment. Incomplete data was adequately addressed in about half of the trials and this information was unclear for about 30% of the trials. Due to extensive heterogeneity across interventions, populations, and outcomes, the results were summarized only qualitatively.9 of the 12 trials showed some evidence of effectiveness compared to a control or other intervention group, with persistence of effects over the medium and longer-term. Four of these effective interventions were gender-specific, focusing on young females. One study with a small sample size showed positive effects that were not statistically significant, and two studies with larger sample sizes reported no significant effects of the family-based intervention for reducing alcohol misuse.
AUTHORS' CONCLUSIONS: In conclusion, in this Cochrane systematic review we found that that the effects of family-based prevention interventions are small but generally consistent and also persistent into the medium- to longer-term.
青少年酒精滥用问题引发了卫生服务机构、政策制定者、预防工作者、刑事司法系统、青年工作者、教师和家长的关注。
系统评价基于家庭的普遍性预防项目在预防18岁及以下学龄儿童酒精滥用方面的有效性证据。对之前发表的Cochrane系统评价的一部分内容进行更新。
从之前的Cochrane评价中选取截至2002年的相关证据。通过MEDLINE、Cochrane对照试验中心注册库、EMBASE、CORK项目和PsycINFO数据库检索到2010年7月的后续研究。
纳入评估基于家庭的普遍性预防项目并报告18岁及以下学生饮酒结果的随机试验。两名评价员筛选了已识别记录的标题/摘要和全文。
两名评价员使用预先定义的提取表独立提取相关数据。评估偏倚风险。
纳入12项平行组试验。试验报告质量较差,只有20%的试验报告了充分的随机化方法和项目分配隐藏情况。约一半的试验对不完整数据进行了适当处理,约30%的试验该信息不明确。由于干预措施、人群和结局存在广泛异质性,结果仅进行了定性总结。12项试验中的9项显示,与对照组或其他干预组相比有一定的有效性证据,且在中期和长期效果持续。其中四项有效的干预措施针对特定性别,侧重于年轻女性。一项样本量较小的研究显示出积极效果,但无统计学意义,两项样本量较大的研究报告基于家庭的干预措施在减少酒精滥用方面无显著效果。
总之,在本Cochrane系统评价中,我们发现基于家庭的预防干预措施效果较小,但总体上是一致的,并且在中期到长期也持续存在。