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2008 年 9 月至 2009 年 9 月,波兰华沙男男性行为者中的甲型肝炎和甲型肝炎病毒/艾滋病毒合并感染。

Hepatitis A and hepatitis A virus/HIV coinfection in men who have sex with men, Warsaw, Poland, September 2008 to September 2009.

机构信息

Department of Hepatology and Acquired Immunodeficiences, Warsaw Medical University, Warsaw, Poland.

出版信息

Euro Surveill. 2011 Aug 25;16(34):19950.

PMID:21903035
Abstract

We describe the epidemiology and characteristics of hepatitis A among men who have sex with men (MSM)who had been hospitalised due to the infection in Warsaw, Poland, from September 2008 to September 2009. A total of 50 men were analysed; their median age was 28 years (range: 17–43). None had travelled to hepatitis A-endemic regions during the six months before hospitalisation nor had they been vaccinated against hepatitis A. Of the 50 men, 40 had been tested before hospitalisation or on admission for the presence of anti-HIV antibodies: six were coinfected with HIV.The six HIV-positive MSM were significantly older than those who were HIV negative – median age: 37 years(range: 26–43) versus 28 years (range: 17–43); p=0.02.No difference in disease severity or the duration of hospitalisation was observed, however, between the two groups. Our study underlines the need to screen MSM for hepatitis A and to vaccinate them against hepatitis A. Given the ages of the MSM in our study,we recommend that this be carried out in Poland when the MSM are aged 20–35 years. This should apply not only to MSM with multiple casual partners but also to those in monogamous relationships.

摘要

我们描述了 2008 年 9 月至 2009 年 9 月期间因感染在波兰华沙住院的男男性行为者(MSM)中甲型肝炎的流行病学和特征。共分析了 50 名男性;他们的中位年龄为 28 岁(范围:17-43)。在住院前的六个月内,他们均未前往甲型肝炎流行地区旅行,也未接种甲型肝炎疫苗。在 50 名男性中,有 40 名在住院前或住院时接受了抗 HIV 抗体检测:其中 6 名合并感染了 HIV。6 名 HIV 阳性 MSM 明显比 HIV 阴性的 MSM 年龄大——中位年龄:37 岁(范围:26-43)与 28 岁(范围:17-43);p=0.02。然而,两组之间的疾病严重程度或住院时间没有差异。我们的研究强调了对 MSM 进行甲型肝炎筛查和接种甲型肝炎疫苗的必要性。鉴于我们研究中的 MSM 的年龄,我们建议在 MSM 年龄为 20-35 岁时在波兰进行此项筛查。这不仅适用于有多个偶然伴侣的 MSM,也适用于一夫一妻制关系的 MSM。

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