Department of Chemical Engineering, Inha University, 253 Yonghyun-Dong, Nam-Ku, Incheon 402-751, South Korea.
J Chromatogr A. 2012 Apr 6;1232:37-42. doi: 10.1016/j.chroma.2011.08.054. Epub 2011 Aug 22.
Polymer-confined ionic liquids were used for the separation of phenolic acids from natural plant extract by utilizing an anion-exchange mechanism. They were synthesized using molecular imprinting technique to reduce non-directional ion-ion interactions during anion-exchange and other interactions with interference substances that could decrease selectivity. A suitable sorbent for phenolic acid separation could be identified based on the adsorption behaviors of phenolic acids on different polymer-confined ionic liquids. Thus, the developed ionic liquid-based molecularly imprinted anion-exchange polymer (IMAP) achieved high recovery rates by solid-phase extraction of phenolic acids from Salicornia herbacea L. extract: 90.1% for protocatechuic acid, 95.5% for ferulic acid and 96.6% for caffeic acid. Moreover, the phenolic acids were separable from each other by repeated solid phase extraction cycles. The proposed method could be used to separate other phenolic acids or organic acids from complex samples.
聚合物限制的离子液体被用于通过利用阴离子交换机制从天然植物提取物中分离酚酸。它们是通过分子印迹技术合成的，以减少阴离子交换过程中无定向的离子-离子相互作用和与可能降低选择性的干扰物质的其他相互作用。可以根据酚酸在不同聚合物限制的离子液体上的吸附行为来鉴定用于酚酸分离的合适吸附剂。因此，通过从盐角草提取物中进行酚酸的固相萃取，开发的基于离子液体的分子印迹阴离子交换聚合物（IMAP）实现了酚酸的高回收率：原儿茶酸为 90.1%，阿魏酸为 95.5%，咖啡酸为 96.6%。此外，酚酸可以通过重复的固相萃取循环彼此分离。该方法可用于从复杂样品中分离其他酚酸或有机酸。
