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金诺芬(瑞得)治疗强直性脊柱炎

[The treatment of ankylosing spondylitis with auranofin (Ridaura)].

作者信息

Grasedyck K, Schattenkirchner M, Bandilla K

机构信息

Medizinische Klinik, Universitätskrankenhaus Hamburg-Eppendorf.

出版信息

Z Rheumatol. 1990 Mar-Apr;49(2):98-9.

PMID:2190436
Abstract

Auranofin has no influence on axial skeleton manifestation of ankylosing spondylitis, neither on clinical complaints, nor on function and inflammatory parameters. Peripheral arthritis is possibly influenced positively, but this cannot be stated definitely because of the low number of cases in this study. This question must be analyzed in larger collectives, as alternatives to conventional therapy are needed for the treatment of peripheral joint involvement of ankylosing spondylitis.

摘要

金诺芬对强直性脊柱炎的中轴骨骼表现没有影响,对临床症状、功能及炎症指标均无影响。它可能对周围关节炎有积极影响,但由于本研究中病例数量较少,无法明确肯定这一点。由于治疗强直性脊柱炎的周围关节受累需要传统疗法的替代方法,因此必须在更大规模的群体中分析这个问题。

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Renal diseases in ankylosing spondylitis: review of the literature illustrated by case reports.
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Drugs. 1992 Oct;44(4):585-603. doi: 10.2165/00003495-199244040-00006.