Poole-Wilson P A
Department of Cardiac Medicine, National Heart and Lung Institute, London, United Kingdom.
Drugs. 1990;39 Suppl 4:25-8; discussion 41-2. doi: 10.2165/00003495-199000394-00006.
The objectives of treatment for patients with chronic heart failure are the prevention of the initial occurrence, the alleviation of signs and symptoms, the delay of the progression of damage to heart muscle and the reduction of the mortality rate. Many drugs are used in severe heart failure. Current controversy is concerned with which drugs to use in patients with mild heart failure or with left ventricular dysfunction. There is a trend towards the earlier introduction of an angiotensin-converting enzyme inhibitor combined with a diuretic.
慢性心力衰竭患者的治疗目标是预防疾病初发、缓解体征和症状、延缓心肌损害进展以及降低死亡率。重度心力衰竭会使用多种药物。目前的争议在于轻度心力衰竭患者或左心室功能不全患者该使用何种药物。现在有一种趋势是更早地使用血管紧张素转换酶抑制剂联合利尿剂。