Shafran S D
Department of Medicine, University of Alberta, Edmonton, Canada.
J Otolaryngol. 1990 Jun;19(3):158-68.
The ability of bacteria to resist the inhibitory and lethal actions of antibiotics is a major clinical problem, and has been observed with every antimicrobial agent. In this article, the major mechanisms of antibiotic resistance are reviewed, and the clinical relevance of such resistance in selected bacteria is discussed.
细菌对抗生素的抑制和致死作用产生抗性的能力是一个重大的临床问题，并且在每种抗菌药物中都有观察到。本文回顾了抗生素抗性的主要机制，并讨论了这种抗性在特定细菌中的临床相关性。
