Department of Microbial Pathogenesis, Dental School, University of Maryland, Baltimore, MD, USA.
Virulence. 2011 Sep-Oct;2(5):445-59. doi: 10.4161/viru.2.5.17724. Epub 2011 Sep 1.
Increasing attention has been focused on understanding bacterial biofilms and this growth modality's relation to human disease. In this review we explore the genetic regulation and molecular components involved in biofilm formation and maturation in the context of the Gram-positive cocci, Staphylococcus aureus. In addition, we discuss diseases and host immune responses, along with current therapies associated with S. aureus biofilm infections and prevention strategies.
人们越来越关注于理解细菌生物膜及其与人类疾病的关系。在这篇综述中，我们探讨了革兰阳性球菌金黄色葡萄球菌中生物膜形成和成熟的遗传调控和分子组成。此外，我们还讨论了与金黄色葡萄球菌生物膜感染相关的疾病和宿主免疫反应以及当前的治疗方法和预防策略。
