Department of Digestive Surgery, Hôpital Saint-Antoine AP-HP, University Paris VI (Pierre et Marie Curie), 184 rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France.
Langenbecks Arch Surg. 2012 Jan;397(1):11-7. doi: 10.1007/s00423-011-0848-x. Epub 2011 Sep 16.
Surgery is the only curative option in the treatment of ulcerative colitis. Despite advances in the medical management surgery is required in about a third of patients.
In the acute setting surgery is indicated when medical treatment fails to improve an episode of acute severe colitis. The intervention of choice is a staged colectomy with end ileostomy and preservation of the rectal stump in the first instance. Indications for elective surgery are failure of medical therapy and malignant transformation. The surgical options include conventional proctectomy with ileostomy or a Kock's continent ileostomy and colectomy with an ileorectal anastomosis. The current gold standard is restorative proctocolectomy with ileal pouch-anal anastomosis. Most frequently the technique includes a J pouch with a stapled anastomosis and temporary faecal diversion with a loop ileostomy. Laparoscopic pouch surgery is a feasible and safe option with an excellent cosmetic result.
Although the morbidity remains significant after surgery, the quality of life is good with a satisfactory long-term functional outcome.
手术是治疗溃疡性结肠炎的唯一治愈选择。尽管医学治疗取得了进展,但仍有约三分之一的患者需要手术。
在急性发作时,如果药物治疗未能改善急性重度结肠炎,就需要手术。首选的治疗方法是分期结肠切除术,行末端回肠造口和直肠残端保留。选择性手术的指征包括药物治疗失败和恶性转化。手术选择包括常规的直肠切除术和回肠造口术,或 Kock 的可控回肠造口术和结肠切除术以及回直肠吻合术。目前的金标准是回肠袋肛管吻合术。最常见的技术包括带有吻合钉的 J 袋和临时回肠造口术进行粪便转流。腹腔镜袋手术是一种可行且安全的选择,具有极佳的美容效果。
尽管手术后的发病率仍然很高,但生活质量良好,长期功能预后令人满意。