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宽叶库塔瑞阿和加勒比埃克索斯特马提取物对恶性疟原虫的体外抗疟活性。

In vitro antimalarial activity of Coutarea latiflora and Exostema caribaeum extracts on Plasmodium falciparum.

作者信息

Noster S, Kraus L

机构信息

Lehrstuhl für Pharmakognosie, Universität Hamburg, Federal Republic of Germany.

出版信息

Planta Med. 1990 Feb;56(1):63-5. doi: 10.1055/s-2006-960885.

DOI:10.1055/s-2006-960885
PMID:2192380
Abstract

The medicinal plants, Coutarea latiflora Sesse & Moc. ex. DC. (Hintonia latiflora Bullock) (Rubiaceae) and Exostema caribaeum (Jacq.) Roem. et Schult. (Rubiaceae) were examined for antimalarial properties. Among different crude solvent extracts of the stem bark, the hydrolysed ethyl acetate extracts were shown to have the most potent in vitro antimalarial activity. One compound isolated from the ether extract from Exostema caribaeum showed only moderate activity.

摘要

对药用植物阔叶库塔瑞阿(Coutarea latiflora Sesse & Moc. ex. DC.)(宽叶辛托尼亚(Hintonia latiflora Bullock))(茜草科)和加勒比埃克斯特马(Exostema caribaeum (Jacq.) Roem. et Schult.)(茜草科)进行了抗疟特性研究。在茎皮的不同粗溶剂提取物中,水解乙酸乙酯提取物显示出最强的体外抗疟活性。从加勒比埃克斯特马的乙醚提取物中分离出的一种化合物仅表现出中等活性。

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