Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa 296-8602, Japan.
Jpn J Radiol. 2011 Oct;29(8):598-603. doi: 10.1007/s11604-011-0591-9. Epub 2011 Sep 17.
The aim of this study was to perform the phantom experiment and demonstrate the clinical usefulness of tissue quantification using a linear array transducer and acoustic radiation force impulse (ARFI) technology.
For the phantom study, the commercially available Elasticity QA Phantom Model 049 was used. First, we measured the shear wave velocity (m/s) for the four spheres and the background of the phantom. Then, the shear wave velocity at nine sites was measured, with the region of interest being moved gradually from a shallow region (3 mm) to a deeper region (38 mm). For the clinical study, the shear wave velocities of 15 solid breast mass lesions were measured.
The phantom study confirmed the feasibility of quantitative determination of the degree of tissue hardness. Dispersion of the measured values tended to be somewhat increased for the depths of 3 mm and 38 mm. The mean shear wave velocity was 2.07-2.93 m/s for five benign lesions, whereas higher shear wave velocities (n = 2) (7.15, 7.44 m/s) or "X.XX" (unmeasurable state) (n = 7) were found for malignant lesions other than mucinous carcinoma (2.44 m/s).
ARFI tissue quantification is a potentially promising ultrasonographic technique for diagnosing breast lesions.
本研究旨在进行体模实验，展示使用线性阵列换能器和声辐射力脉冲（ARFI）技术进行组织定量的临床应用价值。
对于体模研究，使用了市售的 Elasticity QA Phantom Model 049。首先，我们测量了体模中四个球体和背景的剪切波速度（m/s）。然后，在九个部位测量剪切波速度，感兴趣区域逐渐从浅区（3mm）移动到深区（38mm）。对于临床研究，测量了 15 个实性乳腺肿块病变的剪切波速度。
体模研究证实了定量测定组织硬度程度的可行性。对于 3mm 和 38mm 的深度，测量值的离散度趋于略有增加。5 个良性病变的平均剪切波速度为 2.07-2.93m/s，而恶性病变（除黏液癌，为 2.44m/s）的剪切波速度较高（n=2）（7.15、7.44m/s）或为“X.XX”（不可测量状态）（n=7）。
ARFI 组织定量是一种有潜力的超声诊断乳腺病变的技术。
