Medical University of Graz, Division of Endocrinology and Metabolism, Auenbruggerplatz 15, A-8036 Graz, Austria.
J Neurol Sci. 2011 Dec 15;311(1-2):15-8. doi: 10.1016/j.jns.2011.08.046. Epub 2011 Sep 22.
Rickets, osteomalacia, osteoporosis and myopathy are among the better known consequences of a low to very low vitamin D status. Over the past several years various predominantly epidemiological and prospective cohort studies have found associations between low vitamin D levels and various extraskeletal conditions. These findings may particularly become important over the next years since large proportions of the population have low vitamin D levels. Increasing incidence rates of obesity, adverse life-style factors and active avoidance of sunlight seem to decrease average population mean vitamin D levels further. This article gives a brief overview of known and also less well-established potential detrimental effects of a low vitamin D status.
佝偻病、骨软化症、骨质疏松症和肌肉病都是维生素 D 状态低下至非常低下的一些较为人知的后果。在过去的几年中，各种主要的流行病学和前瞻性队列研究发现，维生素 D 水平低与各种骨骼外疾病之间存在关联。这些发现可能在未来几年变得尤为重要，因为很大一部分人群的维生素 D 水平较低。肥胖症的发病率不断上升、不良的生活方式因素以及对阳光的主动回避似乎进一步降低了人群平均维生素 D 水平。本文简要概述了维生素 D 状态低下已知的和不太确定的潜在有害影响。
