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检测指甲花纹身中的对苯二胺和 2-羟基-1,4-萘醌。

Quantification of p-phenylenediamine and 2-hydroxy-1,4-naphthoquinone in henna tattoos.

机构信息

Department of Dermatology, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria 35016, Spain.

出版信息

Contact Dermatitis. 2012 Jan;66(1):33-7. doi: 10.1111/j.1600-0536.2011.01992.x. Epub 2011 Oct 5.

DOI:10.1111/j.1600-0536.2011.01992.x
PMID:21972791
Abstract

BACKGROUND

Very few studies are available in which the components of henna products used by tattoo artists have been analysed.

OBJECTIVE

The aim of this study was to quantify the amounts of lawsone (2-hydroxy-1,4-naphthoquinone, the active ingredient in henna) and p-phenylenediamine (PPD) in products used by tattoo artists and in commercial henna preparations used as hair dyes or to create temporary tattoos.

METHODS

We used high-performance liquid chromatography to detect and quantify lawsone and PPD concentrations in three products used by henna tattoo artists, 11 commercially available henna preparations, and a batch of henna leaves (Lawsonia inermis).

RESULTS

The henna leaves contained 1.85-1.87% lawsone. Only one of the three preparations used by tattoo artists contained lawsone (0.21-0.35%), and all three were adulterated with PPD (1-64%). Of the 11 commercial henna preparations analysed, nine contained lawsone (1-2%) and two contained PPD (2% and 12%).

CONCLUSIONS

Products purporting to be henna, but that in fact contain no henna, are being offered. Moreover, these products may contain PPD, which is associated with health risks, especially severe allergic reactions.

摘要

背景

目前很少有研究分析纹身艺术家使用的指甲花产品的成分。

目的

本研究旨在定量分析纹身艺术家使用的产品以及作为染发剂或用于制作临时纹身的商用指甲花制剂中的指甲花素(指甲花的活性成分,2-羟基-1,4-萘醌)和对苯二胺(PPD)的含量。

方法

我们使用高效液相色谱法检测和定量分析了三位纹身艺术家使用的三种产品、十一种市售指甲花制剂和一批指甲花叶片(散沫花)中的指甲花素和 PPD 浓度。

结果

指甲花叶片中含有 1.85-1.87%的指甲花素。只有一位纹身艺术家使用的三种制剂中含有指甲花素(0.21-0.35%),且这三种制剂均掺有 PPD(1-64%)。在分析的十一种商业指甲花制剂中,有九种含有指甲花素(1-2%),有两种含有 PPD(2%和 12%)。

结论

目前市面上有一些号称是指甲花的产品,但实际上并不含有指甲花,而且这些产品可能含有 PPD,PPD 会带来健康风险,尤其是严重的过敏反应。

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Contact Dermatitis. 2012 Jan;66(1):33-7. doi: 10.1111/j.1600-0536.2011.01992.x. Epub 2011 Oct 5.
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