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经上皮、地形引导消融治疗 LASIK 瓣或界面并发症所致视觉障碍。

Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications.

机构信息

SynsLaser Kirurgi AS, Tromsø, Norway.

出版信息

J Refract Surg. 2012 Feb;28(2):120-6. doi: 10.3928/1081597X-20110926-01. Epub 2011 Sep 30.

Abstract

PURPOSE

To evaluate the efficacy and safety of a single-step, transepithelial, topography-guided surface ablation in the treatment of visual disturbances including irregular astigmatism and light scattering caused by LASIK flap or interface complications.

METHODS

Seventeen eyes of 16 patients with LASIK flap or interface complications and central residual stromal thickness ≥300 μm were treated with a topography-guided custom transepithelial "no touch" (cTEN) technique using the iVIS Suite 1-kHz excimer laser (iVIS Technology). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refraction, corneal irregularity, ocular higher order aberrations (HOAs), and visual symptoms were analyzed.

RESULTS

Mean 15.9±11.0 months after surgery, mean UDVA improved from 20/87 to 20/25. Mean CDVA improved from 20/28 to 20/19 (P<.001), with 64.7% of eyes gaining two or more lines of CDVA. Mean corneal irregularity index decreased from 25.82 to 20.36 μm (P=.009). Mean root-mean-square (RMS) of total HOAs decreased from 1.30 to 0.49 (P=.042), whereas RMS of the odd-order (3rd and 5th) and even-order (4th and 6th) HOAs decreased from 0.85 to 0.38 (P=.001) and 0.43 to 0.24 (P=.036), respectively. All patients claimed their visual symptoms were better (8 eyes) or cured (9 eyes).

CONCLUSIONS

Corneal regularization and removal of the underlying flap or interface pathology by cTEN ablation appears to be an effective treatment for LASIK flap or interface complications associated with visually disturbing irregular astigmatism and light scattering in cases with sufficient residual stromal thickness.

摘要

目的

评估经上皮、单一步骤、地形引导表面消融术治疗 LASIK 瓣或界面并发症引起的视觉障碍(包括不规则散光和光散射)的疗效和安全性,这些视觉障碍包括 LASIK 瓣或界面并发症和中央剩余基质厚度≥300μm。

方法

使用 iVIS 套件 1-kHz 准分子激光(iVIS 技术)对 16 例 17 眼 LASIK 瓣或界面并发症且中央剩余基质厚度≥300μm 的患者进行经上皮、地形引导的定制“无接触”(cTEN)技术治疗。分析未矫正的远视力(UDVA)、矫正的远视力(CDVA)、屈光度、角膜不规则性、眼高阶像差(HOAs)和视觉症状。

结果

术后平均 15.9±11.0 个月,平均 UDVA 从 20/87 提高到 20/25。平均 CDVA 从 20/28 提高到 20/19(P<.001),64.7%的眼提高了两行或两行以上的 CDVA。平均角膜不规则指数从 25.82μm 降低至 20.36μm(P=.009)。总 HOAs 的均方根(RMS)从 1.30μm 降低至 0.49μm(P=.042),奇数阶(3 阶和 5 阶)和偶数阶(4 阶和 6 阶)HOAs 的 RMS 分别从 0.85μm 降低至 0.38μm(P=.001)和从 0.43μm 降低至 0.24μm(P=.036)。所有患者均自述视觉症状改善(8 眼)或治愈(9 眼)。

结论

对于剩余基质厚度足够的 LASIK 瓣或界面并发症相关的视觉障碍(包括不规则散光和光散射),cTEN 消融术通过角膜规则化和去除潜在的瓣或界面病变,似乎是一种有效的治疗方法。

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