Automated Scheduling, Optimisation and Planning Group, School of Computer Science, University of Nottingham, Nottingham, NG8 1BB, UK.
Bioinformatics. 2011 Dec 1;27(23):3323-4. doi: 10.1093/bioinformatics/btr571. Epub 2011 Oct 12.
The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking.
Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3.
Infobiotics Workbench 是一个集成的软件套件,包含系统和合成生物学的模型规范、模拟、参数优化和模型检查。模块化的模型规范允许轻松创建包含许多隔室和反应的大规模模型。可以使用随机模拟或数值积分来模拟模型,并在时间和空间上进行可视化。可以使用进化算法优化模型参数和结构,并使用概率模型检查计算模型属性。
适用于 Linux、Mac 和 Windows 的源代码和二进制文件可在 http://www.infobiotics.org/infobiotics-workbench/ 上获得;根据 GNU 通用公共许可证 (GPL) 版本 3 发布。