Department of Food and Nutrition, College of Human Ecology, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.
Nutr Res Pract. 2011 Aug;5(4):329-36. doi: 10.4162/nrp.2011.5.4.329. Epub 2011 Aug 31.
Obesity contributes to an increased risk for chronic diseases, including diabetes, cardiovascular diseases, and certain types of cancer. The prevalence of obesity has increased in Korea. We compared the clinical and dietary characteristics of obese adults (n = 30, 17 men and 13 women, mean age 29.9) to those with a normal weight (n = 15, 8 men and 7 women, mean age 26.5). We determined lipid profiles, fasting blood sugar (FBS), blood pressure, and serum free fatty acid (FFA). Dietary intake was estimated using a food frequency questionnaire (FFQ) and a 3-day dietary record. Exercise patterns and average alcohol intake were determined. The average body mass index was 28.3 kg/m(2) in the obese and 21.2 kg/m(2) in the normal weight groups. The obese group had significantly higher levels of total cholesterol, LDL cholesterol, and triglycerides, lower levels of HDL cholesterol, and higher blood pressures compared to the normal weight group. FBS was not significantly different between the two groups. The obese group had significantly more subjects with metabolic syndrome (26.7%) compared to the normal weight group (0%). Serum FFA levels tended to be higher in the obese (P = 0.087). No significant difference in caloric intake was observed between the two groups. No differences in carbohydrate, protein, or fat intake between two groups were observed from the FFQ. However, results from the 3-day dietary record showed that the percentage of energy from fat was significantly higher in the obese group. The frequency and amount of exercise did not differ between the two groups. Alcohol consumed per drinking episode was significantly higher in the obese group. These results confirm that excessive weight is associated with disturbances in lipid metabolism in these fairly young and otherwise healthy adults. Dietary factors, including higher fat intake and alcohol consumption, seem to be contributing to the obesity of these subjects.
肥胖会增加患慢性病的风险，包括糖尿病、心血管疾病和某些类型的癌症。韩国的肥胖患病率一直在上升。我们比较了肥胖成年人（n = 30，17 名男性和 13 名女性，平均年龄 29.9 岁）和体重正常的成年人（n = 15，8 名男性和 7 名女性，平均年龄 26.5 岁）的临床和饮食特征。我们测定了血脂谱、空腹血糖（FBS）、血压和血清游离脂肪酸（FFA）。饮食摄入情况通过食物频率问卷（FFQ）和 3 天饮食记录来评估。还确定了运动模式和平均酒精摄入量。肥胖组的平均体重指数为 28.3 kg/m2，正常体重组为 21.2 kg/m2。与正常体重组相比，肥胖组的总胆固醇、LDL 胆固醇和甘油三酯水平显著升高，HDL 胆固醇水平显著降低，血压也更高。两组之间 FBS 无显著差异。肥胖组有代谢综合征的患者明显多于正常体重组（26.7%比 0%）。肥胖组的血清 FFA 水平较高（P = 0.087）。两组之间的热量摄入没有明显差异。从 FFQ 中观察到两组之间碳水化合物、蛋白质或脂肪的摄入量没有差异。然而，3 天饮食记录的结果显示，肥胖组的脂肪供能百分比明显更高。两组之间的运动频率和运动量没有差异。肥胖组单次饮酒的酒精摄入量明显更高。这些结果证实，超重与这些相当年轻且其他方面健康的成年人的脂质代谢紊乱有关。饮食因素，包括更高的脂肪摄入和饮酒，似乎是导致这些受试者肥胖的原因。
