向着病毒基因组注释标准迈进：2010 年 NCBI 注释工作坊报告。
Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop.
机构信息
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20892, USA.
Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
出版信息
Viruses. 2010 Oct;2(10):2258-2268. doi: 10.3390/v2102258. Epub 2010 Oct 13.
Improvements in DNA sequencing technologies portend a new era in virology and could possibly lead to a giant leap in our understanding of viral evolution and ecology. Yet, as viral genome sequences begin to fill the world's biological databases, it is critically important to recognize that the scientific promise of this era is dependent on consistent and comprehensive genome annotation. With this in mind, the NCBI Genome Annotation Workshop recently hosted a study group tasked with developing sequence, function, and metadata annotation standards for viral genomes. This report describes the issues involved in viral genome annotation and reviews policy recommendations presented at the NCBI Annotation Workshop.
DNA 测序技术的改进预示着病毒学的新时代的到来，可能会使我们对病毒进化和生态学的理解产生巨大飞跃。然而，随着病毒基因组序列开始填满世界生物数据库，至关重要的是要认识到这一时代的科学前景取决于一致和全面的基因组注释。考虑到这一点，NCBI 基因组注释研讨会最近组织了一个研究小组，负责为病毒基因组制定序列、功能和元数据注释标准。本报告描述了病毒基因组注释所涉及的问题，并回顾了在 NCBI 注释研讨会上提出的政策建议。
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