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乌干达西南部个人和医疗机构因素与分娩梗阻及其不良结局的关系。

Individual and health facility factors and the risk for obstructed labour and its adverse outcomes in south-western Uganda.

机构信息

Division of Social Medicine and Global Health, Department of Clinical Sciences, Lund University, CRC, Entrance 72, 205 02 Malmo, Sweden.

出版信息

BMC Pregnancy Childbirth. 2011 Oct 14;11:73. doi: 10.1186/1471-2393-11-73.

Abstract

BACKGROUND

Obstructed labour is still a major cause of maternal morbidity and mortality and of adverse outcome for newborns in low-income countries. The aim of this study was to investigate the role of individual and health facility factors and the risk for obstructed labour and its adverse outcomes in south-western Uganda.

METHODS

A review was performed on 12,463 obstetric records for the year 2006 from six hospitals located in south-western Uganda and 11,180 women records were analysed. Multivariate logistic regression analyses were applied to control for probable confounders.

RESULTS

Prevalence of obstructed labour for the six hospitals was 10.5% and the main causes were cephalopelvic disproportion (63.3%), malpresentation or malposition (36.4%) and hydrocephalus (0.3%). The risk of obstructed labour was statistically significantly associated with being resident of a particular district [Isingiro] (AOR 1.39, 95% CI: 1.04-1.86), with nulliparous status (AOR 1.47, 95% CI: 1.22-1.78), having delivered once before (AOR 1.57, 95% CI: 1.30-1.91) and age group 15-19 years (AOR 1.21, 95% CI: 1.02-1.45). The risk for perinatal death as an adverse outcome was statistically significantly associated with districts other than five comprising the study area (AOR 2.85, 95% CI: 1.60-5.08) and grand multiparous status (AOR 1.89, 95% CI: 1.11-3.22). Women who lacked paid employment were at increased risk of obstructed labour. Perinatal mortality rate was 142/1000 total births in women with obstructed labour compared to 65/1000 total births in women without the condition. The odds of having maternal complications in women with obstructed labour were 8 times those without the condition. The case fatality rate for obstructed labour was 1.2%.

CONCLUSIONS

Individual socio-demographic and health system factors are strongly associated with obstructed labour and its adverse outcome in south-western Uganda. Our study provides baseline information which may be used by policy makers and implementers to improve implementation of safe motherhood programmes.

摘要

背景

在低收入国家,产程梗阻仍然是产妇发病率和死亡率以及新生儿不良结局的主要原因。本研究旨在探讨个体和医疗机构因素在乌干达西南部产程梗阻及其不良结局中的作用。

方法

对乌干达西南部六家医院 2006 年 12463 份产科记录和 11180 名妇女记录进行了回顾性分析。应用多变量逻辑回归分析来控制可能的混杂因素。

结果

六家医院的产程梗阻患病率为 10.5%,主要原因是头盆不称(63.3%)、胎位不正或位置异常(36.4%)和脑积水(0.3%)。产程梗阻的风险与特定地区(伊辛戈罗)的居民身份(调整后比值比[AOR]1.39,95%置信区间[CI]:1.04-1.86)、初产妇状态(AOR 1.47,95%CI:1.22-1.78)、曾有一次分娩经历(AOR 1.57,95%CI:1.30-1.91)和 15-19 岁年龄组(AOR 1.21,95%CI:1.02-1.45)相关。作为不良结局的围产儿死亡风险与研究地区以外的五个地区相关(调整后比值比[AOR]2.85,95%置信区间[CI]:1.60-5.08)和多产妇状态(AOR 1.89,95%CI:1.11-3.22)相关。没有带薪工作的妇女产程梗阻的风险增加。与无梗阻产妇相比,梗阻产妇的围产儿死亡率为 142/1000 总分娩,而无梗阻产妇为 65/1000 总分娩。梗阻产妇发生产妇并发症的几率是非梗阻产妇的 8 倍。梗阻性难产的病死率为 1.2%。

结论

个体社会人口和卫生系统因素与乌干达西南部的梗阻性难产及其不良结局密切相关。我们的研究提供了基线信息,决策者和执行者可以利用这些信息来改善安全孕产方案的实施。

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