National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand.
J Nat Prod. 2011 Oct 28;74(10):2143-50. doi: 10.1021/np200429b. Epub 2011 Oct 13.
Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7β,15α-dihydroxy-22(29)-hopene (8), 3β,7β-dihydroxy-22(29)-hopene (9), 3β-acetoxy-15α-hydroxy-22(29)-hopene (10), 3β,7β,15α,22-tetrahydroxyhopane (11), 3β-acetoxy-7β,15α,22-trihydroxyhopane (12), and 7β,15α,22-trihydroxyhopane (13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.
从虫生真菌 Hypocrella sp. BCC 14524 中分离得到了 7 个新的羊毛甾烷型三萜，即 hypocrellols A-G（1-7），和 6 个新的霍烷型三萜，分别为 7β,15α-二羟基-22(29)-霍烯（8）、3β,7β-二羟基-22(29)-霍烯（9）、3β-乙酰氧基-15α-羟基-22(29)-霍烯（10）、3β,7β,15α,22-四羟基霍烷（11）、3β-乙酰氧基-7β,15α,22-三羟基霍烷（12）和 7β,15α,22-三羟基霍烷（13）。这些新化合物的结构通过 NMR 光谱和质谱数据分析进行了阐明。1 的结构通过 X 射线晶体学得到了确证。
