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等离子体表面改性技术在提高血管移植物血液相容性中的应用:综述。

Application of plasma surface modification techniques to improve hemocompatibility of vascular grafts: A review.

机构信息

Polymer Engineering Faculty, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.

出版信息

Biotechnol Appl Biochem. 2011 Sep-Oct;58(5):311-27. doi: 10.1002/bab.50. Epub 2011 Oct 3.

DOI:10.1002/bab.50
PMID:21995534
Abstract

Surface modification using plasma processing can significantly change the chemical and physical characteristics of biomaterial surfaces. When used in combination with additional modification techniques such as direct chemical or biochemical methods, it can produce novel biomaterial surfaces, which are anticoagulant, bioactive, and biomimetic in nature. This article reviews recent advances in improving hemocompatibility of biomaterials by plasma surface modification (PSM). The focus of this review is on PSM of the most commonly used polymers for vascular prostheses such as expanded polytetrafluoroethylene (PTFE), polyethylene terephthalate (Dacron(®) ), and next generation of biomaterials, including polyhedral oligomeric silsesquioxane nanocomposite.

摘要

通过等离子体处理进行表面改性可以显著改变生物材料表面的化学和物理特性。当与其他改性技术(如直接化学或生化方法)结合使用时,可以产生新型的生物材料表面,这些表面具有抗凝血、生物活性和仿生特性。本文综述了通过等离子体表面改性(PSM)提高生物材料血液相容性的最新进展。本综述的重点是对最常用于血管假体的聚合物(如膨体聚四氟乙烯(PTFE)、聚对苯二甲酸乙二醇酯(Dacron®))和下一代生物材料(包括多面体低聚倍半硅氧烷纳米复合材料)进行 PSM。

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