Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences in Olsztyn, Poland.
Lipids Health Dis. 2011 Oct 14;10:178. doi: 10.1186/1476-511X-10-178.
The objective of the present study was to examine the influence of adding various amounts beetroot (Beta vulgaris) crisps on gastrointestinal function, antioxidant status and blood and liver lipid profiles in a high fat diet-induced dyslipidaemic rat model;
The intake of a dyslipidaemic diet increased the serum total cholesterol, total cholesterol-to-HDL-cholesterol ratio, atherogenic index, hepatic total cholesterol and triacylglycerols, suppressed production of short-chain fatty acids and decreased total antioxidant status and blood glutathione peroxidase activity. Oral administration of all tested amounts of beetroot crisps prevented the rise in serum total cholesterol and triacylglycerols levels. The treatment with the addition of 3% crisps also decreased hepatic total cholesterol level and activity of AST in serum. The experimental addition of crisps likewise resulted in a tendency towards a higher total SCFA pool and activity of glutathione peroxidase and a lower serum glucose level (p = 0.080, p = 0.061 and p = 0.067, respectively);
Results of the presented study suggest that the addition of beetroot crisps could alleviate metabolic changes in dyslipidaemic diet-administered rats.
本研究旨在探讨在高脂饮食诱导的血脂异常大鼠模型中添加不同量的甜菜根薯片对胃肠道功能、抗氧化状态以及血液和肝脏脂质谱的影响；
摄入血脂异常饮食会增加血清总胆固醇、总胆固醇与高密度脂蛋白胆固醇比值、致动脉粥样硬化指数、肝总胆固醇和三酰甘油，抑制短链脂肪酸的产生，并降低总抗氧化状态和血液谷胱甘肽过氧化物酶活性。所有测试量的甜菜根薯片的口服给药均可防止血清总胆固醇和三酰甘油水平升高。添加 3%薯片的治疗还降低了血清中天冬氨酸转氨酶和肝总胆固醇的水平。实验添加薯片同样导致更高的总短链脂肪酸池和谷胱甘肽过氧化物酶活性以及更低的血清葡萄糖水平（p = 0.080、p = 0.061 和 p = 0.067，分别）；
本研究结果表明，添加甜菜根薯片可能减轻血脂异常饮食喂养大鼠的代谢变化。
