Wang Z H, Olafsson R, Ingram P, Li Q, Qin Y, Witte R S
Appl Phys Lett. 2011 Sep 12;99(11):113701-1137013. doi: 10.1063/1.3632034. Epub 2011 Sep 14.
Ultrasound current source density imaging (UCSDI) potentially transforms conventional electrical mapping of excitable organs, such as the brain and heart. For this study, we demonstrate volume imaging of a time-varying current field by scanning a focused ultrasound beam and detecting the acoustoelectric (AE) interaction signal. A pair of electrodes produced an alternating current distribution in a special imaging chamber filled with a 0.9% NaCl solution. A pulsed 1 MHz ultrasound beam was scanned near the source and sink, while the AE signal was detected on remote recording electrodes, resulting in time-lapsed volume movies of the alternating current distribution.
超声电流源密度成像(UCSDI)有可能改变对大脑和心脏等可兴奋器官的传统电映射。在本研究中,我们通过扫描聚焦超声束并检测声电(AE)相互作用信号来展示时变电流场的体积成像。一对电极在充满0.9%氯化钠溶液的特殊成像腔室中产生交变电流分布。在源极和汇极附近扫描脉冲1兆赫超声束,同时在远程记录电极上检测AE信号,从而得到交变电流分布的延时体积电影。