Jang Jong Soon, Kwon Soon Kil, Kim Hye-Young
Division of Nephrology, Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
Electrolyte Blood Press. 2011 Jun;9(1):16-22. doi: 10.5049/EBP.2011.9.1.16. Epub 2011 Jun 30.
This study aimed to investigate the influence of different peritoneal dialysis regimens on blood pressure control, the diurnal pattern of blood pressure and left ventricular hypertrophy in patients on peritoneal dialysis. Forty-four patients undergoing peritoneal dialysis were enrolled into the study. Patients were treated with different regimens of peritoneal dialysis: 26 patients on continuous ambulatory peritoneal dialysis (CAPD) and 18 patients on automated peritoneal dialysis (APD). All patients performed 24-hour ambulatory blood pressure monitoring (ABPM) and echocardiography. Echocardiography was performed for measurement of cardiac parameters and calculation of left ventricular mass index (LVMI). There were no significant differences in average of systolic and diastolic blood pressure during 24-hour, daytime, and nighttime between CAPD and APD groups. There were no significant differences in diurnal variation of blood pressure, systolic and diastolic blood pressure load, and LVMI between CAPD and APD groups. LVMI was associated with 24 hour systolic blood pressure load (r = 0.311, P < 0.05) and daytime systolic blood pressure load (r = 0.360, P < 0.05). In conclusion, this study found that there is no difference in blood pressure control, diurnal variation of blood pressure and left ventricular hypertrophy between CAPD and APD patients. The different peritoneal dialysis regimens might not influence blood pressure control and diurnal variation of blood pressure in patients on peritoneal dialysis.
本研究旨在探讨不同腹膜透析方案对腹膜透析患者血压控制、血压昼夜模式及左心室肥厚的影响。44例接受腹膜透析的患者纳入本研究。患者接受不同的腹膜透析方案治疗:26例接受持续性非卧床腹膜透析(CAPD),18例接受自动化腹膜透析(APD)。所有患者均进行24小时动态血压监测(ABPM)和超声心动图检查。超声心动图用于测量心脏参数并计算左心室质量指数(LVMI)。CAPD组和APD组在24小时、白天和夜间的收缩压和舒张压平均值无显著差异。CAPD组和APD组在血压昼夜变化、收缩压和舒张压负荷以及LVMI方面无显著差异。LVMI与24小时收缩压负荷(r = 0.311,P < 0.05)和白天收缩压负荷(r = 0.360,P < 0.05)相关。总之,本研究发现CAPD患者和APD患者在血压控制、血压昼夜变化和左心室肥厚方面无差异。不同的腹膜透析方案可能不会影响腹膜透析患者的血压控制和血压昼夜变化。