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具有分级纳米结构的磁性介孔碳酸羟基磷灰石微球用于药物输送系统。

Magnetic mesoporous carbonated hydroxyapatite microspheres with hierarchical nanostructure for drug delivery systems.

机构信息

State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China.

出版信息

Chem Commun (Camb). 2011 Nov 28;47(44):12215-7. doi: 10.1039/c1cc15190h. Epub 2011 Oct 14.

DOI:10.1039/c1cc15190h
PMID:21998826
Abstract

Magnetic mesoporous carbonated hydroxyapatite microspheres have been fabricated hydrothermally by using CaCO(3)/Fe(3)O(4) microspheres as sacrificial templates. The high drug-loading capacity and sustained drug release property suggest that the multifunctional microspheres have great potentials for bone-implantable drug-delivery applications.

摘要

磁性介孔碳酸羟基磷灰石微球是通过水热法以 CaCO(3)/Fe(3)O(4)微球为牺牲模板制备的。高载药量和持续药物释放性能表明，多功能微球在骨植入药物输送应用中具有巨大的潜力。

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