Department of Dermatology and Cutaneous Surgery, College of Medicine, University of South Florida, Tampa, FL, USA.
Int J Dermatol. 2011 Nov;50(11):1309-1322. doi: 10.1111/j.1365-4632.2011.05096.x.
Many dermatological disorders have a psychosomatic or behavioral aspect. Skin and brain continually interact through psychoneuroimmunoendocrine mechanisms and through behaviors that can strongly affect the initiation or flaring of skin disorders. It is important to consider these mind-body interactions when planning treatments for specific skin disorders in individual patients. Mind-influencing therapeutic options that can enhance treatment of skin disorders include standard psychotropic drugs, alternative herbs and supplements, the placebo effect, suggestion, cognitive-behavioral methods, biofeedback, and hypnosis. When individual measures do not produce the desired results, combinations of drugs or addition of non-drug therapies may be more successful. Psychophysiological skin disorders may respond well to non-drug and drug therapies that counteract stress. Treatment of primary psychiatric disorders often results in improvement of associated skin disorders. Psychiatric disorders secondary to skin disorders may also require treatment. Therapeutic options for each of these are discussed.
许多皮肤病都有身心或行为方面的因素。皮肤和大脑通过神经免疫内分泌机制以及可能强烈影响皮肤疾病发生或加剧的行为不断相互作用。在为个别患者的特定皮肤疾病制定治疗方案时，考虑这些身心相互作用非常重要。可以增强皮肤疾病治疗效果的、受心理影响的治疗选择包括标准精神药物、替代草药和补充剂、安慰剂效应、暗示、认知行为方法、生物反馈和催眠。当个别措施未产生预期效果时，药物联合治疗或添加非药物疗法可能会更成功。可能会对对抗压力的非药物和药物治疗有良好反应的心理生理性皮肤疾病。原发性精神疾病的治疗通常会导致相关皮肤疾病的改善。继发于皮肤疾病的精神疾病也可能需要治疗。讨论了每种疾病的治疗选择。
