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连翘酯苷,一种从连翘中分离得到的具有抗氧化和抗菌作用的苯乙醇苷类化合物。

Isoforsythiaside, an antioxidant and antibacterial phenylethanoid glycoside isolated from Forsythia suspensa.

机构信息

Université Pierre & Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire, UMR 7201 CNRS, 4 Place Jussieu, 75005 Paris, France; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, PR China.

Université Pierre & Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire, UMR 7201 CNRS, 4 Place Jussieu, 75005 Paris, France.

出版信息

Bioorg Chem. 2012 Feb;40(1):87-91. doi: 10.1016/j.bioorg.2011.09.005. Epub 2011 Oct 1.

Abstract

The isolation, structural elucidation, antioxidant effect and antibacterial activity of isoforsythiaside, a novel phenylethanoid glycoside isolated from Forsythia suspensa, were described. The antioxidant activity was estimated using the 1-diphenyl-2-picrylhydrazyl scavenging activity method and the in vitro antimicrobial activity was evaluated by the microtitre plate method. The results showed that this compound had strong activities. Owing to these properties, the study can be further extended to exploit for the possible application of isoforsythiaside as the alternative antioxidants and antibacterial agents from natural origin.

摘要

从连翘中分离得到的新型苯乙醇苷异连翘脂苷的分离、结构鉴定、抗氧化活性和抗菌活性。采用 1-二苯基-2-苦基肼自由基清除活性法测定抗氧化活性,微量板法测定体外抗菌活性。结果表明,该化合物具有较强的活性。由于这些特性,本研究可以进一步扩展,以探索异连翘脂苷作为天然来源的替代抗氧化剂和抗菌剂的可能应用。

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