Department of Cosmetic Science, Chia-Nan University of Pharmacy and Science, Tainan 717, Taiwan.
Bioorg Med Chem Lett. 2011 Dec 1;21(23):7201-4. doi: 10.1016/j.bmcl.2011.09.052. Epub 2011 Sep 29.
Three new cembranoids crassocolides N-P (1-3), was isolated from the organic extract of a Formosan soft coral Sarcophyton crassocaule. These structures were elucidated on the basis of spectroscopic analyses and by comparison with those previously reported in literature. The cytotoxicity of these compounds toward various cancer cell lines has also been determined.
从台湾产软珊瑚 Sarcophyton crassocaule 的有机提取物中分离得到了三种新的海鞘烷类化合物 crassocolides N-P(1-3)。这些结构是基于光谱分析,并与文献中先前报道的结构进行比较而阐明的。这些化合物对各种癌细胞系的细胞毒性也已被确定。