Cobankara Funda Kont, Erdogan Hilal, Hamurcu Mehmet
Department of Endodontics, Faculty of Dentistry, Selcuk University, Konya, Turkey.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):e149-54. doi: 10.1016/j.tripleo.2011.06.037. Epub 2011 Oct 19.
The objective of this in vitro study was to assess the effect of several chelating agents on the mineral content of root dentin.
Extracted human mandibular incisor roots were prepared and divided into groups according to the following irrigation protocols: 1) 17% ethylenediaminetetraacetic acid (EDTA); 2) 10% citric acid solution; 3) 18% etidronate; 4) 2.25% peracetic acid; 5) and deionized water (control). Dentin chips were obtained (Gates-Glidden nos. 3, 4, and 5). The levels of different minerals were analyzed with the use of inductively coupled plasma-atomic emission spectrometry (ICP-AES).
The chelation agents can create different effects on mineral contents of root dentin, so it is important to know what effects each solution will have on root dentin before their clinical use. In addition, according to the results of this in vitro study, it might be recommended that peracetic acid, in particular, should be used with caution.
本体外研究的目的是评估几种螯合剂对牙根牙本质矿物质含量的影响。
将拔除的人下颌切牙牙根进行处理，并根据以下冲洗方案分组：1）17%乙二胺四乙酸（EDTA）；2）10%柠檬酸溶液；3）18%依替膦酸；4）2.25%过氧乙酸；5）去离子水（对照组）。获取牙本质碎屑（盖茨-格利登钻针3号、4号和5号）。使用电感耦合等离子体原子发射光谱法（ICP-AES）分析不同矿物质的水平。
1）与其他组相比，过氧乙酸显著降低了磷、钾、镁、钠和硫的水平（P < 0.05）。2）在所有螯合溶液中，硫均有不同程度的降低（P < 0.05），过氧乙酸中硫的降低最为明显。3）过氧乙酸、柠檬酸和EDTA组中的钙水平显著降低（P < 0.05）。4）柠檬酸和过氧乙酸组中的锰水平显著降低（P < 0.05）。5）过氧乙酸、柠檬酸和依替膦酸组中的钠和锌水平显著降低（P < 0.05）。
螯合剂对牙根牙本质的矿物质含量会产生不同影响，因此在临床使用前了解每种溶液对牙根牙本质的影响非常重要。此外，根据本体外研究结果，尤其建议谨慎使用过氧乙酸。
